avastin

[lucymullis]

My ca125 rose for about 6 months.  I was waiting to enroll in a parp trial; however, in May it shot up to 1100 and I felt I could not wait any longer so I started chemo again June 1 with carbo, taxol and avastin. (first recurrence since my diagnosis in 2006)  I enrolled in GOG 213 and am getting the avastin.  My scan on June 30 showed that the areas had disappeared and my ca125 is now 14.5.

I am concerned that some patients on avastin find their cancer returns much more aggressively.  I attended the ovca national convention in DC in July and heard some discussion on this.  The only research I have seen on it has been done on animals but related that this was the result.

I am enrolled in GOG 213 and continue with the avastin until it no longer works.  This is my question to you:  Would you recommend I do this or discontinue the avastin?  

[lucymullis]

this was meant for the doc forum.  However, I'd love to know your experiences/opinions.

[marie3B]

I am glad you posted this here.  I had not known that Avastin could cause the cancer to return more aggressively.  Having been on Avastin myself, I wish I had been aware before using it.  Marie

[nyc lady]

So sorry to hear this.  Sorry that it came back and that you are dealing with this all over again.  I really hoped that the trial you were on was going to keep you in remission forever!!!

I know someone on avastin now and she has developed new masses but the original have stayed stable.

I hope that they find the right chemo for you.

Pam