Hi, I am 41 years old. In chronic respiratory failure. On O2 24 hours/day. First CT scan showed interstitial/aveolar disease and thickening, second CT scan 5 months later showed, none of those, but several small nodules, possible fibrosis and atelectasis, but no active lung disease, then 3 months later CT scan showed atelectasis, no nodules, no mention of aveolar or interstitial lung disease or fibrosis. In looking for answer to why hypoxic.....dr. (who has two certifications in sleep studies) has concluded that I have severe sleep apnea (55 episodes/hour desat to 74%) and it is carrying over to daytime and that the ct scans with their varied results mean nothing. Had positive methylcholine challenge...yet last pft relatively normal with midflows decreased at 64% of predicted and airway resistance slightly increased- signifying mild obstructive airway disease with no change with ventolin/atrovent. I am confused. Is it normal for the cat scans to be so varied? Is it normal for sleep apnea to cause daytime hypoxia? I have episodes with cough, wheezing, flushing and high blood pressure..putting me in hospital....multiple times. Have you ever seen anything like this before? Do you have any ideas for me what might be going on and what to do? I am having a hard time believing it is all sleep apnea related. Please help.