Cushings or hyperparathyroidism

[bjones345]

I have various symptoms frequent urinations sweating, frequent thirst,high blood pressure , blood sugar high sometimes, severe muscle cramps spasms,acne, naseua,no appetite,exhausted, feeling like gonna have seizure somettimes and troublke talking!! my acth level was 5, 24 hour free cortsol was 146 range 11-84;
my acth level was 5
24 hour free cortsol was 146 range 11-84
cortsol/creatinine ratio   range  7-45 mine was 67
24 hour creatinine range 800-2000 mine was 2193
cortisol serum  rznge from 4.3- 22.4 mine was 23.2
lh rang from 1.5-9.3 mine was 3.5
fsh range from 1.4-18.1 mine was 1.0
tsh- range 0.350-5.500 mine was 1.418
t4 range from 4.5-12.0 mine was 6.6
t3 rangs 85-205 mine was127
hepatacarboxylp,24 hur 7 range 0-4
coproporph 24 hour 70 0-24
coproporh 3 24 hour 84 0-74
calsium 10.4 range 8.5-10.6
glucagon 32 range 40-130
my phosphuras has also been low

I have not been able to work due to the muscle cramps its like my bod is not regulating?

[bjones345]

I had a 24 hour urin aldosterone u timed was 12 range from 2-21 ; high salt 0-14
i was on 8 grams of salt and 50 mg of of metoprolol  could this have altered the results my renun was 1.51; ptassium 4.1

[bjones345]

yes they are porphyrins, I saw a hematologist and did another 24 hour porphyin test and he told me I did not have porhyria so whast would cause these to be high?
I had a cat scan of adrenals the other day and they showed nothing, my endo ordered another 24 hour cortisol and im waiting on results for 2 24 hour urine test one for 54-aa I think to check for carcinoid and a chromogranin a blood test and another 24 hour urin for metanephrins and catacolmines,

[val1198]

"I have various symptoms frequent urinations sweating, frequent thirst,high blood pressure , blood sugar high sometimes, severe muscle cramps spasms, acne, naseua, no appetite, exhausted"

Those are also symptoms of primary aldosteronism.  Suggest you get an aldosterone/renin blood test.  Also, check your potassium level.

[Mark Lupo, M.D.]

I am not sure what some of those are -- porphyrins perhaps? -- so cannot comment on that.  There is no definite lab evidence of parathyroid -- the cortisol is high and needs additional evaluation by an endocrinologist to see if this is cushings.