Greg

[peaceful man]

Hi Everyone,
I am responding to this site for support related to my thyroid. I began hypothyroid treatment about 4 yrs. ago.While living out west the last 2- 3 years my TSH levels were generally between 3.5- 5.0 (aprox) and I still had symptoms. I take 112 mcg Synthroid. A couple times the doc tries to increase to 125 mcg but I just couldn't tolerate. I would begin to feel great for about 5 days or so and then began to feel worse-- with anxiety, more sleep problems, and just feeling hyper, and tired. It seems that I still have hypo symptoms at 112 mcg and then get hyper at 125 mcg. One doctor out west suggested I alternate dosages or even just take 125 mcg once or twice a week. Does any of this make sense to anyone, or have you experienced this?  I now live in NC and still need to discuss this with my new doc. I also have had very inconsistent sleep throughout all this even when avoiding caff, exercising, relaxing, etc. Does anyone know of effective sleep meds for thyroid issues?

Thanks for listening!  Greg

[Mark Lupo, M.D.]

I have had some patients alternate between two doses and do well.  Another option (perhaps more simple) would be to take 1/2 tablet once a week of the 125mcg dose (and take a whole tab the other days).

Poor sleep can have many etiologies -- I tend to avoid sleep aids and work with a sleep specialist to see what the exact problem is....

[NadiaPost]

I had a similarly bad reaction when being switched from 112 to 125, only instead of sleeplessness it was headaches.  The alternating between the 112 and 125 worked for me, still some headaches in the first few weeks but good after I was done adjusting.  I was told that because the synthroid is slow acting it is safe to take different doses from day to day and the result is having roughly 119mcg in your system.  

[msfergy]

Xanax helps me.