Hashitoxicosis?

[amykat07]

Hi, I saw an endo last week because for the last couple years I have been experiencing issues with my thyroid. I am unbelievably fatigued and hot, and I mean really hot, all of the time. It seems to never get any better. I've experienced some other symptoms but those are the ones that make my life hell. Graves disease runs in my family on my mothers side in most of the women. My original blood test showed a TSH of 0.01. My test this week showed a TSH of 6.28, Free T4 of 0.67 and Free T3 of 3.58 with my TPO anitbodies was extremely high. The ultrasound of my thyroid showed a good amount of scar tissues. I was just wondering if anyone knows what is going on with my thyroid? I am experiencing the symptoms of hyperthyroidism but my blood shows something else altogether. Not to mention its drastic change. My endo diagnosed me with Hashitoxicosis. I can't seem to find a wealth of knowledge on it and was just wondering if someone could give me the run down and also tell me what you think about the blood work. I just started Levothyroxine today. From what I understand that is for hypothyroidism. Is this going to me even more susceptible to heat? I don't think I could tolerate it.

[amykat07]

Hi Mark,
Further lab tests on my antibodies revealed that my thyroid peroxidase antibodies are high and my thyroid stimulating immunoglobulin antibodies were over 900 (the scale for normal went to 9). That seems unbelievably high. Since being put on Levothyroxine I have been even more miserable than before. I'm pretty certain I had an allergic reaction one night, stomach cramps when I wake up, menstrual bleeding everyday since I started the medicine (even though I'm on bc and regular) as well as being even more hot and tired than before. What should I do now?

[Brucergoldberg]

Mark,  can you elaborate?  I barely take any levo .015 yet I go from hypo to hyper every third or 4 th day.  I have heard the odds of being a man with hashimotos is rare, but to have hashimotos and swing opposite the same odds as winning the lottery....

[Mark Lupo, M.D.]

The immune system is attacking your thyroid - the initial presentation was hyper, either from a transient thyroiditis or Graves.  Now it is hypo, like Hashimoto's. Would consider testing TSI and TBII antibodies (graves markers) to see if these are positive -- ie, help predict if you are more likely to be permenantly hypo or be at risk for swinging back/forth (hashitoxicosis).