Symptoms don't match diagnosis

[Dotti439]

For 55 years I have always been slim and fit, very active.  In one year, with no change in my diet or exercise, I gained 25 pounds, developed a low, husky voice, lost the outer 1/3 of my eyebrows.  My cholesterol went from 200 to 280, my bone density got worse.  I barely had enough energy to finish a work day.  My eyes are puffy, I wake up feeling as tired as I was when I went to bed. My blood pressure is less than 100/50, my heart rate is in the 60's.   I have been to MANY doctors, including endocrine and here's the problem.  My T3,T4 are low normal, my Thyroid antibody is 600...but my TSH is <0.01.  One doctor totally ignored my symptoms and put me on Tapazole to 'slow' my thyroid.  Within one month I could not lift my head off the pillow and almost lost my job.  Can ANYONE explain this to me?? I think I need synthroid but no doctor will listen to me.

[Dotti439]

Thank you for answering , Dr. Lupo.  I had a total hysterectomy including my ovaries out.  When I did have periods, they were always irregular.  I also had cystic ovaries.  They did check my ACTH and Cortisol and Insulin levels and they were all normal.

[Mark Lupo, M.D.]

addendum

what I mean by pituitary is low thyroid due to a pituitary problem -- that would be consistent with your symptoms, but this is not common.

[Mark Lupo, M.D.]

Sounds like a potential pituitary problem -- would ask the endocrinologist if a pituitary evaluation (prolactin, ACTH, cortisol, IGF-1, FSH/LH and perhaps MRI scan) has been done to see if this is the case.  

Usually the TSH is not this low however, so I agree the labs are most consistent with subclinical hyperthyroidism (? due to atypical Graves) but if the T4 and T3 are low then the pituitary must be evaluated/