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should I be worry

did my yearly blood work, the results are not so good I'm thinking, eg:
HDL cholesterol 76.0 high mg/dL 40.0  - 60
Cholesterol total 220.0 high mg/dL 0.0 - 200.0  These are Lipid profile

Glucose fasting 75.0 mg/dl 75.0 - 115.0

Basophils%  4.57 high  k/uL % 0.00 - 3.00
Lymphocytes%48.9 high   %  20.0  - 45   These are complete blood count
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875426 tn?1325528416
My grandma had her thyroid removed due to cancer and was on thyroid medication as far as that went.  I believe her big sister may have had peripheral vascular issues as well.  

It was only shortly before she died that my grandma was diagnosed with diabetes and no one talked of her being pre-diabetic to me prior to that late stage in her life.

I don't know, but it seemed between me working with her on diet and the statin drug the doctor had her take, my grandma's cholesterol when I was living with her dropped to below 200.  I can't say for sure the statin wasn't a factor in that overall cholesterol reduction.  I do know she didn't do much exercise because it hurt her to walk due to the peripheral vascular disease.  

But I also know neither of my parents got on well with statin drugs and neither one is taking them.  A different drug, Gemfibrozil worked for awhile with one of my folks for reducing triglycerides.

With a fasting glucose like Thornyrose's, I'm guessing her triglycerides might not be that bad.  I think basophils and lymphocytes would be my focus with the doctor if I were in her shoes.  
Helpful - 0
1756321 tn?1547095325
Yes, i've read about the LDL particle size. I have no worries about this personally since i love my saturated fat.  Saturated fats raise the large subtype of LDL. Having triglycerides of over 140 guarantees a large number of small LDL particle size so i read.

While the article i posted on my first answer from Life extension is from 2008, today atherosclerosis is considered a low-grade inflammatory disease.  But the information is still valid as the causes of inflammation are vast from insulin resistance to smoking to a high inflammatory diet (high carbohydrates (grain and sugars) and excess consumption of omega-6 vegetable oils). Low fat diets are high inflammatory as well. The Mediterranean diet is anti inflammatory and lowers insulin resistance.

Hypothyroidism can lead to high cholesterol levels in the blood as low thyroid hormone slows the liver's ability to process blood.  Genetics is a rare cause of high cholesterol stated to be under 1% of cases.

A very popular magazine in Australia called New Idea has an article which i was very happy to see! A small excerpt...

"Don't be afraid of fat

Christine says fat can actually be good for us. 'For the past 50 years we have been asked to reduce our fat, especially our saturated fats, and statistics show we've reached the recommended targets - but it's not working,' she says. 'Heart disease is out of control and we are still struggling with our weight.  Study after study shows fat was never the problem - in fact, sugar and excess carbohydrates are the true culprits behind obesity and heart disease.'"

Take all this into account and then you don't have to wonder why blogs like this appear...

What I Learned About Heart Disease by DPB Geologist...

"I am a petroleum geologist that was stricken with heart disease in 2007 at a very young age of 48.  I  exercised 5 days a week,  I followed the American Heart Assoc. "low fat" eat healthy grains diet, limited my saturated fat, and I didn't even eat a cholesterol rich egg for over 20 years and still had major blockages in my heart."

Yes well that was a recipe for heart disease wasn't it. Didn't each an egg in 20 years? Poor guy. Eggs are delicious. :)

***

"MYTH: Statin drugs are appropriate for men, women, children and the elderly.

FACT: The only group in which statins have been shown to have even a modest effect is in middle-aged men who’ve already had a heart attack. If you’re not in that group, you’ve got no business on a statin drug." - 8 Cholesterol Myths Your Doctor Still Believes.
Helpful - 0
875426 tn?1325528416
It does seem from recent study announced in the news that LDL has gotten something of a bad rap. ('Lousy' was a term given to LDL to one of my parents years ago during a class given for those with high cholesterol, and HDL was given the term 'happy'.)  

It would appear the size of the LDL particles are a factor- smaller is worse:
http://www.mayoclinic.org/news2011-mchi/6264.html

I do think it's terrible all the pushing of statin drugs with their potential side effects when it's been proven a Mediterranean diet can be at least as effective as those drugs.  

However, as somone who had a grandmother with peripheral vascular disease with sad consequences and she once had, if I recall correctly an overall cholesterol of over 300, I think shooting for an LDL that isn't too high still might not be a bad idea and she did take a statin.

My grandma and her husband ate the same diet, but his cholesterol was very low, while hers was very high.  I believe heredity played a factor in this.

This article: http://www.webmd.com/cholesterol-management/hdl-cholesterol-the-good-cholesterol
indicates the belief that high HDL lowers the risk of heart disease, a reason I think Thornyrose might be encouraged about her number.

I've heard triglycerides being high can lead to plaque formation (and that reducing sugar intake if this number is high is a step to take).  I recently heard the CRP number is very important in regards to heart disease, which is why I'm curious as to what Thornyrose's numbers are.  

Helpful - 0
1756321 tn?1547095325
After a poor diet, hypothyroidism is the second most common cause of high cholesterol.  LDL ships cholesterol from the liver to where its needed in the body and HDL ships cholesterol back to the liver.  All three are essential to life. In short, no good or bad.  

"Atherosclerosis remains a disease of unknown cause. Many factors more important than cholesterol—such as stress, smoking, hypertension, insulin resistance, high triglycerides, diabetes, and low testosterone (in men)—contribute to atherosclerosis and cardiovascular disease.17-19 Despite this, the theory that cholesterol is the dominant villain responsible for atherosclerosis has been promulgated for over 60 years, making the pharmaceutical industry’s anti-cholesterol campaign the most profitable medical myth of all time." - Life Extension -  Alleviating Congestive Heart Failure with Coenzyme Q10

"The name alone sounds so encouraging: HDL, the “good cholesterol.” The more of it in your blood, the lower your risk of heart disease. So bringing up HDL levels has got to be good for health.

Or so the theory went.

Now, a new study that makes use of powerful databases of genetic information has found that raising HDL levels may not make any difference to heart disease risk. People who inherit genes that give them naturally higher HDL levels throughout life have no less heart disease than those who inherit genes that give them slightly lower levels. If HDL were protective, those with genes causing higher levels should have had less heart disease." - New York Times - Doubt Cast on the ‘Good’ in ‘Good Cholesterol’

  
Helpful - 0
875426 tn?1325528416
Wow, your HDL is EXCELLENT!  HDL, the part of the lipid panel sometimes known as happy cholesterol, is believed to fight what is sometimes called lousy cholesterol (LDL).  It can be raised by exercise and eating healthy things, such as pistachio nuts or the plant sterols they put in certain spreads, such as Benecol.   It is thought to reduce risk of stroke.  Excellent number on your HDL!

What was your LDL number?  What was your triglyceride number?  Did you get a CRP number?

Your fasting blood sugar looks like it was within normal range- not too low and definitely not too high.

Your basophils and lymphocytes are both part of a differential white blood cell count.  I have an old lab book, 2nd edition by Frances Fischbach called, 'A Manual okf Laboratory Diagnostic Tests'.  

It says regarding basophils, that their count is something studied when it comes to allergic reactions and there's a tie between when a person's basophils are high and blood histamies in high concentration.  

Have you been suffering from allergies lately?

Now, that's not the only thing it says about high basophils, and I recommend you check with your doctor about your number.  You should also check with your doctor about your high lymphocytes.  The doctor should be apprised and look for any symptoms you may have in their quest for diagnosis of what's wrong in your body.

About your high lymphocytes, there are a variety of things that can cause them to be high.  Conditions my old lab book lists which can cause an increase in lymphocytes:
"(a) Most viral upper respiratory infections
(b) Other viral diseases such as mumps, pertussis, infectious mononucleosis, infectious hepatitis, viral pneumonia, and measles
(c) Bacterial infections such as tuberculosis, brucellosis, syphilis, and healing infections
(d) Hormonal disorders such as hypthyroidsism and hypoadrenalism
(e) Lymphocytic leukemia, lymphocytic lymphosarcoma, leukosarcoma
(f) Diarrhea"  
Helpful - 0
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