I feel as though I am going crazy. I have done many tests (most negative)through my current doctor. I am 49 yrs old. I had a complete hysterectomy at 25. Have not been on HRT since 2/2006. I have aching joints, muscle tenderness, breast tenderness, bloating, mood swings, depression, no motivation, and my legs hurt after walking only a short distance. I found out I have Type II diabetes and am on Metformin (500mg). I have also found small knots in my legs.