First let me apologize, I am a cardiac RN and find myself on the patient end of the spectrum with severe GI distress and am questioning my own knowledge. I have been dealing with unreal lower abdominal pain with an urgency to have a bowel movement on a daily basis for three years. It gets so bad that I can be sitting in traffic for example and have a sudden onset of lower abd pain and urgency, and if I am not in a bathroom in literally 10 seconds I become diaphoretic and almost lose consciousness from the pain. Over the past 6 months it has gotten much worse, even affecting my job. I have had persistent nausea for the past 6 months, with loose, urgent, sometimes bloody bowel movements, continuous lower abd cramping and aching, and have lost 30lbs unintentionally in the past 4 months with no lifestyle changes. Sometimes the pain is relieved with a bowel movement but other times after a "bad day" I am cramping and nauseous all night. I have never had any constipation, all stools are loose. I had no insurance and so finally was just able to have my colonoscopy yesterday, and the GI doc doing the procedure said it looked normal. No biopsies were taken. However I was sick with a URI about a month and a half ago and was on a 10 day course of prednisone and the severity of my GI symptoms eased considerably but still trouble me. What I am wondering is if there could be another pathology for my symptoms even though the colonoscopy looked ok? Is it possible that it could be an inflammatory bowel condition in 'remission'? This has been running my life for the past 6 months and a bother for 3 years and I am desperate for suggestions. I am taking Hyoscyamine and Imodium daily. Thanks for reading my lengthy post, any feedback would be greatly appreciated!