I am 52 years old, have been taking Synthroid (0.075) daily for many years, and have developed a progressively worsening cough. The cough is productive and becomes progressively worse in the morning approx. an hour after taking the Synthroid, subsiding in the late afternoon. (I drink approx. 3 cups of coffee in the mornings as well.) I have been tested for asthma and was found to be borderline. I take Pulmicort but find it of little use. My feeling is this cough is related to my thyroid medication but I cannot quit taking it as my thyroid was removed (left and partial right lobectomy) in 1986 and it is prescribed as replacement therapy, plus my doctor denies there being any possibility of an allergic reaction to the medication. I am wondering if anyone else out there has experienced shortness of breath, hoarseness, a cough which at times wakes you up from a sound sleep, gasping for air. I work out 3 times a week (yes, I cough through those workouts)and yet if I run for a bus I am totally exhausted and cough to try to catch my breath. Walking up even one flight of stairs produces this effect as well. Does this sound familiar to anyone out there?