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Breast Cancer Community

This patient support community is for discussions relating to breast cancer, biopsy, genetics, chemotherapy, hormone therapy, lumps, lumpectomy, lymph node dissection, lymphedema, mammograms, mastectomy, radiation therapy, reconstruction, and self exams.
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herceptin/with congestive heart failure

by PRISSY8, May 11, 2008 08:28PM
im gonna receive herceptin along with  doesetaxel and karboeplatin. iwas diag. with infiltrating ductual carcinoma and intraductal carcinoma had a simple mascetomy no lymph node involvement, estrog neg. progestronneg but her+3 hr2 what do you think of this approch?


This discussion is related to The effect of chemotherapy on her2/neu     cancer.
Member Comments (1)

by Fernando Roque, MD, May 11, 2008 09:18PM
To: PRISSY8
Hi.  I'm assuming here that a sentinel lymph node biopsy was done along with the simple mastectomy.  If only simple mastectomy was done without any form of lymph node sampling, you cannot be absolutely sure that no lymph node was involved.

Anyway, assuming that there really is no lymph node involvement, the appropriateness of giving chemotherapy after surgery would depend on the size of the primary tumor.  If the tumor is 0.5 cm or less, no additional chemotherapy is needed.  If the tumor is greater than 0.5 cm in size, then chemotherapy plus herceptin is appropriate treatment, even if the nodes are negative for tumor.
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