Precancerous skin lesions: Skin lesions called actinic keratoses, which appear as rough, scaly patches on your skin, can increase your skin cancer risk.
Fair skin: People with less pigment in their skin are more likely to get skin cancer. Those who freckle and burn easily are at an increased risk.
Lots of cumulative sun exposure
A weakened immune system: Including HIV/AIDS, HPV, or if you are taking immunosuppressant drugs after an organ transplant
Been sunburned many times, or have had severe sunburns
Moles: Skin cancer is likely to form on moles
Been exposed to toxic materials like arsenic
Vacationed or live in an area at high elevation: UV radiation is more intense at high elevations because it isn't as scattered by the atmosphere.