What to take to feel motivated again

[Dee]

I keep reading that i wont feel motivated to do anything when i start going through detox. is there anything i can take to help with that? and what exactly is this new drug called bup?

[spook]

Dextroamphetamine is a dangerous mix with parnate,because of potentiation of subsequent dangerous side effects,,like sub arachnoid hemorrhage(bleeding brain)from high blood pressure.
If you can get the dextroamphetamine use it with the tyrosine.
If you can get the parnate use it with the tyrosine
DO NOT MIX PARNATE AND DEXTROAMPHETAMINE.
I have and WOW I got zapped,no problems,slight headache next morning.
The problem of the mix is greatly overstated,in fact the BOOK says cheese can do the same(in this case it is the monoamine "tyromine"in cheese.It also says to avoid Avocados,bannana skins?,TCA`s,SSRI`s,alcohol,pethidine,Tryptophan(but does not mention tyrosine)look the list is endless you name it PARNATE potentiates its effects both good and bad.Lets hope the DMT crowd do not here about this ,they are always predosing with some crappy herbal MAOI.
Current stats show 15 per Million people DIE as a result of MAOI interactions,Some people have taken 15 tablets (150mg)a day because they liked the buzz and showed no signs of hypertension.
I think it is the only AD left that stimulates Dopamine to a significant degree,and because my depression was caused by lack of Dopamine,it worked well.Maybe they will ban it if people read all this and doctors start getting requests for it specifically.
Parnate was considered suitable for Severely depressed in-patients under close supervision,who had failed to respond to other AD`s(Antidepressants).
However Presciption products guides,now only list it as any other AD,so their is no Restrictions,in fact they call it a non-hydrazine MAOI(very informative)what it is ,is an AMPHETAMINE,but if the Pharmacuetical companies Say that,then the GOVT eyes of suspicion will be aroused along with the Doctors.
Doctors in general do not understand the neurochemical inbalance that differentiates one Depression from another,some people need more Serotonin other Noradrenaline and me Dopamine.
What I was wondering about is the Box that the tablets come in lists a few of the more important things to avoid and one of those is eating Bannana skins?I mean who the hell eats the skin and what is in the skins?I remember an urban myth about scraping the pulp from bannana skins drying and smoking(mello yellow,not MDA)however research into the Psychoactive constituent of bannana skins reveals nothing,I know they are very bitter.
Anyway the first time I had a Strong coffee with Parnate I got a rush similar to an XTC tab coming on.
The first time I used methadone(20mg IV)I almost had an orgasm,I hit the floor and my heart was pounding.
I have not taken Parnate for about 2 years now,but if I wanted a decent AD I know what to ask for.
I know of other interactions of common legal drugs that are at par with Schedule 1 drugs Euphoria,but I think it is my responsibility to keep them a secret,at least for now.
Drugs are not the answer.
life is for living.
My days of experimenting are coming to a conclusion..........

[spook]

The reason the implant stopped him using heroin is because it stops the heroin from getting him high and so theirs no use in using.It is going to be hard for him to get it out isn`t it?.It is stuck in his stomach.
I have heard of Naltrexone stopping the craving and believe this to be a Placebo response,Also if the naltrexone is bound to the receptor how can Endorphins bind and what happens if they have an accident or something and are in severe pain,what will stop the pain.Certainly not Opioids.Apparently Dopamine provides BASELINE analgesia as experienced by STRAUGHT people.Endorphins are really for crisis pain as occurs in all animals.
Craving is possibly different to compulsive thinking,the craving component may be mediated by Nicotinic acid Receptors,which are somehow modified indirectly by the Naltrexone,I do not know.And the repetative thinking Via Basal gangia-Acetylcholine overload(termination of mentation,see above)
I cannot Prescribe,I am not Registered to prescribe to HUMANS.I am not a Doctor only a Scientist.Even Albert Hoffman,tried his LSD-25 a second time after accidently absorbing some through his skin.I don`t think the 60`s would have happened if he did not~you ask why I do these experiments on myself,would you give to an animal that which you would not take yourself?If only the people knew what suffering these creatures endure in Laboratories all around the world,so some Pharmaceutical companies can make more money by releasing something like ULTRAM/PROZAC/ETC/ETC they would never take a new drug again.
God gave us all the chemicals we need to survive,god put the Opium poppy on this earth,so if our endorphins did not suffice we need not suffer,Peyote cactus to expand our visions and consciousness during sacred ceremonies,etc,etc.I have my own religion,I take what I want,when I want.Who is this Modern Medicine man who just seems to make people sicker?.We are at the beginning of a revolution as the current generation gives way to the next,we are the flowers of the future,they are the poison in our minds.

[FlowerChild11601]

Hi Mike!  My name is Maryanne and I am the one who went to see Dr Gooberman last month (actually in January).  It worked well for withdraw symptoms (the bup, clonidine and baclofen) with little discomfort.  However, I am a chronic pain person and found myself in severe pain with no relief.  I used Alleve, hot baths, massage etc. and finally started to take opiates "here and there" for pain relief but not everyday.  After one month, that lead me back to every day use.  I know I will need to visit Dr Goob again to get off them but that leaves me with the chronic pain issue again and how to get around it.  I hear some people say they just deal with the pain and would rather be clean.  I wish that could be me but I have a job, house, family etc that will not stop with my pain.  I wish you good luck and please feel free to ask any questions.  God Bless, Maryanne

[Gloria]

Parnate (Tranylcypromine sulfate) and Nardil (Phenelzine Sulfate) are MAO (monoamine oxidase) inhibitors.  Their mechanism of action is that they reversibly bind to MAO, reducing its activity, thus resulting in increased levels of neurotransmitters (including dopamine, epinephrine, and norepinephrine).  In medicine, we know that most depressive illnesses are triggered by a decrease in one, or several of the neurotransmitters.  Currently, we do not have tests that can pinpoint which neurotransmitter, or group of neurotransmitters, a patient is deficient in.  That is why for most, medicating depression is done by trial and error.  Parnate is an excellent drug to treat resistant depression.  The reason it is not used as a first-line drug is because as Spook mentioned, it has potentially fatal interactions with dietary tyramine; plus, drugs with sympathomimetic or serotonergic properties.  Due to Parnate's long half-life (the time it takes to be excreted fully from your body), it has the potential to cause a fatal reaction (due to a dietary interaction) up to two weeks after stopping the drug--longer if the patient has been on the medication for years.  What foods contain tyramine?  Try taking this medication and avoiding caffeine, chocolate, beer, wine, liquor, aged cheese, bananas, any cured sausage (bologna, pepperoni, salami, summer sausage), anything smoked, yeast extracts, anything pickled, avocadoes, soy sauce...  This is not a complete list, nor does it include all the medications that Parnate can interact with.  I know a physician that had gradually, in minute doses, added some items from the list to her diet while on Parnate.  She allowed herself one cup of coffee daily.  For whatever reason (there had been no change in the coffee, etc.), she suffered a near-fatal, hypertensive crisis following a few sips of coffee one morning.  That is the main reason that people do not hear/know about Parnate or Nardil.  Have you ever looked on the back of cold/sinus medications and there is a warning:  "Do not take this medication if you are on a MAO inhibitor?"  Surprisingly, you will see this warning on many OTC meds.  Parnate is an energizing antidepressant and is a good medication.  Unfortunately, the risks far outweigh the benefits in most cases.  As for the "normal" dosage of Parnate, usually 15 mg. twice a day to start; then increase to a max of 60 mg/day.  I hope this has been helpful.  Maria.

[mike d.]

Hi...thanks for your response...I do have a few questions if you don't mind? I take it you skipped the implant because of your pain issues? Did they "strongly encourage" the implant? I'm 10 days clean,(oxycontin)feeling ok but tired. How long did you take the other meds? I'm wondering if they are adding to the fatigue problem. What did you think of your treatment at Dr.Gooberman's office.On one hand I thought it was great to get the help during that crucial first 3-5 days.On the oher hand I didn't really get very helpful answers to my inquiries. I don't know what I expected.Anyway...thank you much for your time, you too Brighty and Spook:)

[Brighty]

Spooks comments indicate to me that it is a psychological crutch... nothing wrong with that at all !! My concerns were for those ... specifically heroin users... they are often beyond the beyond... you know what I mean... those you realize are pretty handy with a syringe :-)) ... they have used with the implant, overdosed and died. Knowing their resistance to reason or normal emotions I think it's  a possible death sentence to give them an implant. In cases like yours I think you would want to weigh the benefits vs. the risks... and the risks for pill users seem more minimal to me. Congratulations being 10 days off the meds !!! God bless you in your efforts. Love, Brighty