Veterinary neurologists agree that Frontline and Revolution are the safest anti-flea and tick products as far as seizures are concerned, however in a very small percentage there is a possibility that either of the products could cause seizures. But it is very uncommon.
Therefore, it may be coincidental that your dog had a seizure after using Frontline, or Frontline could have been the cause of the seizure.
It would be best to have your dog evaluated for epilepsy by your vet. This would involve bloodwork to check for metabolic, endocrine and infectious causes and other blood tests such as a Lyme,or Ehrlichia check. His heart would also need an evaluation, since syncope can appear as a seizure. Other causes of seizures are abnormalities in the brain either from trauma, or a lesion in the brain.
Thank you for your information. I will take him to his vet today. His mother also had seizures as a pup though but my dog is already almost one year. However, the hind leg weakness seems odd to me. He seems to be doing better today, eating more and walking faster. Thanks again!