I have pain in my joints that seems to go in cycles. Started seeing a rhumatologist but no diagnosis yet. I have had an eleveated CRP and Sed rate for the the entire time testing has been going on. All the common auto immune and infectious stuff is negative. I have alternating results with liver functions and thyroid function (sometimes WNL, sometimes not), Enlarged spleen without a reason. I alo have unrelated back issues (spondylolisthesis) which seems worse during these episodes. I have had 2 burst packs of prenisone and felt 100% better for a couple of days, then right back to constant pain. What could this be? I am beginning to feel like a head case!