Your TPO and TG are well above range, indicating Hashimoto's Thyroiditis.
What thyroid treatment are you on and why is it NOT working? What type of doctor is treating you???
Your tTG is well above range as well indicating Celiac
Disease. You are obviously NOT on a gluten-free diet.
*More on this later.
Your ferritin (storage iron) is mid-range/OK.
Your MCHC is above range, possibly indicating hemolytic anemia with symptoms of varying degrees of anemia, fatigue, splenomegaly and so on.
Partial splenectomy would be the preferred treatment.
You may also have estrogen dominance ( causing an imbalance in the estrogen/progesterone ratio and leading to fibrocystic breasts, polycystic ovaries and more).
You may need to modify your diet and avoid xeno-estrogens and boost your progesterone levels by taking bio-identical progesterone cream.
*Most Hypothyroid & Hashimoto's sufferers have gluten intolerance or Celiac's and may not even know it!
The gluten molecules-mainly from gmo grains- resemble the TPO(Thyroid Peroxidase - an enzyme necessary for the signalling Thyroid hormone production) molecules and thus the immune system in its response against gluten, attacks the TPO in the Thyroid also!
You must go gluten-free as a trial ASAP!
Gluten is in everything! Envelopes, shampoos, cosmetics, creams, lotions, sauces, condiments, soups, beer,
play-dough, and many other products often not listed as an ingredient or listed with a different name!
I'm puzzled. With so many strong and clear indicators
and test results, why are you not being treated appropriately for your conditions.
Estrogen dominance might be a challenge for many doctors, but it's not rocket science either.
Celiac's no excuse !
Hashimoto's/Hypothyroidism just needs some attention to get thyroid function properly regulated, by frequent monitoring and adjusting thyroid meds as needed.
Prolonged under-treated thyroid function may be responsible for the development and onset of autoimmune conditions, including connective tissue disease (one of thyroid's lesser known functions is to activate enzymes responsible for cellular debris removal, thus leading to autoimmunity) and perhaps esophageal hypertrophy ( possibly as result of diminished motility because of low thyroid function).
Please post details regarding current treatments and other pertinent information.
My opinion is to have the reverse T3 (RT3) test, before increasing the Levothyroxine, which would make matters much worse, should your RT3 result comes back high.
Reverse T3 is converted directly from T4 and Levethyroxine is synthetic T4.
Any increase as a trial should be in T3, like Cytomel or whatever brand T3 comes in.
Please refer to my previous post.
From your most recent results your FT3 is rather low and it ideally should be in the upper one third of the reference range -->4.95-6.80 if my math is correct.
The high MCHC should be addressed ASAP, as the iron infusions-while improving your iron status- may have be doing very little to correct the suspected "functional" anemia, a definite factor in hypothyroidism, which BTW maybe the underlying cause of the suspected high RT3.
I feel that there are a lot of simple connections that your
doctors are not making.
That is sad :( because you may be stuck in limbo and unnecessarily suffering greatly.