Dear Terry: Microcalcifications are small calcium deposits found within the breast tissue and these occur normally. There are different types of microcalcifications, and based on their pattern on the mammogram it gives the radiologist clues as to their cause. For instance microcalcifications that are more scattered are probably due to a benign (non-cancerous) cause, a "cluster" of microcalcifications may increase concern that there may be an underlying abnormality. This could be many things but generally requires further investigation. Most of the time, these turn out to be benign. A BIRAD 4 means that there is a suspicious abnormality. Most category 4 abnormalities are benign but may require biopsy since this category can be malignant in 25-50% of cases.