Patient:Maria,very active ex.athlete,excellent condition.
Birth 08/1936
Other Disases:serotonine problems,panic crisis etc,degenerated athritis.
TOTAL HYSTERECTOM 1985
Abortion 1965
Total thyroidectomy 2004 (no cancer found) treated since 2004 with T4 (PROBLEMS WITH THIS PILL)
Period cycle 1947(11 years old)
One son caesarian 1964
Regular mammographys every 1-2 years after 1985
Last mammography Janyary 2005 no tumor found
Date of tumor suspition: September 2005, mammography
Operation on end of september 2005
T1 NO MO (stage 1)
Final Diagnosis :
Left breast Quatrandectomy(low exterior quarter of the left breast) plus partial lumpectomy
Type: Mixte type carcinoma, invasing Lobular classic and Ductal, 1.7cm (1,7X1,5) ,compact, not specified type,GradeII(6),
The lobular infiltrating carcinoma with linear cell structure.
Resection margins free
Excised Lymph Nodes 8, free of cancer (with the SLN negative)
ER-ica = Hi-Score 240
PR-ica =Hi-Score 60
c-erb-b2=positive(+)
20-25% off the cells with high positive expression on the antibody CB11against Her2/Neu(Cerb-b2)(score3+)(NO FISH!)
Negative for antibody DO7 against Proteine p53
Negative against Cathepsine D
35-40% of the cells positive cytoplastic expression to the antibody against the proteine pS2
5-10% of the cells with positive nuclear expression to the antibody against the cell-groath factor Ki67(M1B1)
75-80% of the cells with strongly positive expression against the ER-ica
25-30% of the cells with midle positive expression against pPR-ica
What should she do?Please help me,i am her son, Jerry