Has anyone experienced their depression coming back if they catch some sort of bug? I had a sore throat and muscle aches, soreness and my depression seems to come back, even though I take antidepressants, I get lethargic, fatigue , no motivation to do anything and I sleep all day, I feel very drowsy. It seems like this happens every week or so, like I have a bad immune system. I don't remember feeling depression when I was sick when I was younger.