Hello. nursegirl is right, you must discuss this with a doctor. We are fellow sufferers and cannot prescribe what medication you should take. Hope you do get professional help.
Take care.
This is something you have to talk to your doctor about. Most antidepressants are okay to take with Methadone, but there may be other considerations. Are you asking because of depression? Have you been diagnosed with depression? If I may ask, what do you take the Methadone for, pain management? Or addiction treatment?