I suffer from Major depression and I also know other's esp. in my family that suffer from Major Depression and/or Seasonal Depression. From my experience, Everyone is unique and while their are characteristics that some people with depression may have in common; there are also some characteristics or traits that are unique to that person. For example: some people with depression are happy to not be alone and appear happy when others are around. On the other hand, many people who are depressed act withdrawn and keep to themselves even when others are around.
As far as medication their are all kinds of antidepressants and most people end up trying atleast a few different meds before finding the one that works best for them.
I don't know anyone that has depression that I would be afraid to leave them alone. The only reason I can think of to worry about leaving a person with depression alone is if they were suicidal and in that case they need professional care asap. Hope this helps. I agree with hensley258 your question is worded in a confusing way, so if this doesn't help you may want to reword your original concerns.
I got confused. Are you asking to gain knowledge about a loved one with Major Depression, or do you suffer yourself and want to know what other people feel?
how does it effect you in particular.
The only person I know is me and of course the other members on this forum.
I guess I could give you examples from my experience, but I don't know if that would be the same as if you talked to a non-sufferer like you wanted to.
Just say the word and I will be happy to at least tell you how it effects me.