Not enough information in your post. Safe by itself? Safe with other medications? Safe with insulin? Safe for, with, or what? Try a Google search on 'how safe is byetta' for about 116,000 hits.
I used Byetta for a long time and I am not an expert or medical person. You are best to get the information from your doctor. Before I started using Byetta, I had to take classes from a nurse on how I had to inject Byetta into my stomach. It was prescribed by my Doctor. Byetta has side effects reported by some people but I had no problems with it other than the expense. It does give you a feeling of fullness and it has a nickname (Spit). That is because it was made with saliva of the Gila monster. A lot of people who are not diabetics have been trying to get the prescription for it because it is also know to have a positive side effect (Helps people to quit smoking). Hope this helps you with your question.
Ruben