You have had a pretty comprehensive evaluation, including a CT scan and colonoscopy. This would rule out many of the major disorders - such as colitis or inflammatory bowel disease.
More specialized testing can be considered - including sending the stool off for malabsorption or blood tests looking for celiac disease.
If the tests continue to be negative, treatment for irritable bowel syndrome can be considered with tricyclic antidepressants, antispasmodic agents, or antibiotics like Rifaximin.
If the discomfort is upper GI in origin, an upper endoscopy can be considered.
These options can be discussed with your personal physician.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_
I forgot to add - since you had a "complete" blood work by an endo - have him run a GTT.
If you pass the fasting glucose, they won't run a GTT or a A1C unless you ask.
You can have diabetes with an FPG under 126 (or even "normal) if the 2HR post-prandial is over 200. That would still be diabetes, would still cause you to lose water and sugar (calories, and hence weight) due to renal losses when the glucose spikes high, still can cause damage to the body, and still indicates pancreas problems.
I hope not, but if it were me, I'd ask for the GTT.
I had a normal FPG and was diagnosed with IGT based on a GTT. The GTT is more sensitive.
Unexpected weight loss and dry mouth (loss of water?) - check for diabetes.
Diabetes is due to the pancreas malfunctioning - it can also be malfunctioning in the exocrine (digestive) sense, not just the endocrine (diabetes, other hormones) sense.
Thanks,
Were you any more hungry than usual? Im eating more just because I would like to gain weight (its not working) but Im not really hungrier and I thought that was also a symptom of diabetes