Primary schlerosing cholangitis is diagnosed via ERCP or MRCP. A liver biopsy may sometimes be necessary. There are many other reasons that can raise the liver enzymes - and PSC is relatively uncommon. You may want to explore the other possibilites first.
As I do not deal with many transplant patients, I do not know if PSC would preclude you from a kidney donation.
Regarding colitis - I do not believe that should be an obstacle for donation.
These questions need to be discussed with your transplant surgeon or personal physician.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
Medical Weblog:
kevinmd_b
I just wanted to add that despite the above, I am in great physical condition, my blood pressure is excellent, as is my cholesterol. All my other tests that the specialists did to see whether I was in good enough physical condition to be able to donate a kidney came back very good. I have done various marathons and triathlons, and did Ironman Canada back in 2003, so I think physically, my body has adapted very well to my colitis.
I am a mother of a son that had PSC. I believe that the average case of PSC is 10-12 years before a liver transplant is necessary. My son's time was much less. Also something else to consider....the meds (prograf) tht you MUST take after a transplant are very hard on the kidneys. My son is 27 now and is 4 years post transplant. If you do have PSC and need a liver in the future.......there is an evaluation process to get on the organ list to receive a liver. Will they pass you if you have only 1 kidney? Just a few thoughts for you to consider.