I am female and suffer from both irritable bowel with diarrhea and irritable bladder which causes me to run back and forth to the bathroom day and night. I try to watch what I eat and avoid foods that seem to trigger IBS symptoms such as nuts, broccoli, etc. I take Immodium when I have to. I take Vesicare for the bladder symptoms. Is it unusual for a person to have both problems? I have had both of these since I was a child. I wonder if I have been misdiagnosed. I have a great niece who had been misdiagnosed with IBS, but she has Crohn's disease. I had a colonoscopy about 5 years ago, but haven't had an upper GI. Sometimes my abdomen hurts so badly that I break out in a cold sweat and my abdomen actually feels hot to touch on the lower left side. My stools are always either the diameter of my little finger or loose and watery. Could there be another explanation for my having the same kinds of problems for my bladder and my colon? Off and on for years my bilirubin serum has been high and my spleen is sometimes enlarged upon examination. I don't have hepatitis. I had a very large parathyroid adenoma removed recently that had been causing big problems with my bones and kidneys. It had rendered one half of my thyroid useless because it was embedded in it. One half of my thyroid had to be removed. I was born 3 months premature and have had problems with my colon since I was a baby.