MTHFR C677T????

[projectbaby]

Hey all!!!!  I just wanted to ask what this means???? I tested positive for one copy of this, but has anyone else????? and what did they do for you?????
Jacquie

[Jenbug]

Well,  since my ob doctor disagrees with me getting a homocysteine screen I have made an appointment with my family doctor who is an internal medicine doctor.  Because MTHFR is really a problem for a person in more than just fertility and pregnancy.  He should know some stuff about it and maybe he will let me get the test.  I see him on Thursday.  

[ashort]

After all that I've been reading I think once I become pregnant I think I'm going to ask my RE to give me the name of a good perintologist.  I think it's better to be safe then sorry.  I'm sorry to hear about everyone's losses.  I'm also taking a baby aspirin, folbic, and prenatals.  

Jenbug-  I had my homocysteine levels checked about 10 weeks after my m/c.  I would say it's a good idea for you to.  I don't think age makes a difference with MTHFR b/c you always have that gene mutation.  It gives me hope that you have 3 healthy boys!  I'm 30 the good thing is we still have time....

Good luck everybody!

[kls60]

i have mthfr c677t and i have had three misscariages ( i just had the third last week and i go back to doc on monday to see if hcg level is back down to 0) this last pregnancy i was taking neevo, 2 - 800mg folic acid and a baby asprin in the morning and neevo, 2 more 800 mg folic acid and prometrium at night.  I did not make it any further with this pregancy than the other two.  my hcg level did get a lot higher but i still miscarried at 6-7 weeks.  my obgyn said at this point he has done all he can do and is ready to refer me to a specialist.  my homocysteine level was not high but i did test abnormal for the mthfr mutation.  my father died at 46 from a clot and had a stroke at 42 and after going over family history my obgyn had a feeling i would test abnormal for this mutation.  i really thought after finding out the problem and taking these vitamins and asprin would help me stay pregant.  what do you suggest.  does anyone know what else i can do or should i make a consultation and go see a specialist.  

[Jenbug]

Oops sorry for the empty space!  To answer your question... no I never had any difficulty conceiving or carrying a pregnancy until this year. I am only 34 y/o.  I don't know if age is a factor or not in all of this.  I am currently not pregnant.  I had a missed miscarriage about 6 weeks ago and a D & E and I am still waiting for my period.  I am not sure now would be a good time to get my homocysteine screening, but I am anxious to see what it might be.  

[ashort]

No I don't think you are worng for wanting your homocysteine levels checked. My RE said I should have mine checked during my pregnancy.  It is VERY important!  Did you have any problems coneiving your boys?

[Jenbug]

Wow!  It was so wonderful to hear everyone's story.  I learned so much.  I am compound heterozygous for MTHFR.   I found this out after 2 miscarriages this year.  After a lot of research, I asked my OB to allow me to have a homocysteine screen because I read that the compound heterozygotes can have the same risks and symptoms of homozygotes.  She disagreed and started getting defensive and irritated at me so I backed down.  I don't know if I am going to try to have anymore children because we already have 3 precious boys (lots of work!!).  But if we do, I want to get a doctor that will take this more seriously.  

Thanks so much for sharing- especially baby123.  That was the best explanation I have heard and confirmed all my research.  I am going to print this out for my DH to read.

Do you think that I am right in wanting to get the homocysteine screen?  And, pregnancy aside, what should one do in my situation to be healthy for the rest of my life living with this problem.  In other words, to protect my heart and health should I be taking extra B vitamins etc...