I've never tried Domperidone, but the only meds that helped me were Nexium or Kapidex taken twice daily. I tried prevacid and it was very brief because it just didn't work for me :(
Also, I use to take one Kapidex/Nexium PLUS some Amitriplyn, but I knocked the amitriplyn out of my regimen. Either way, it offered more good days then bad.
The best medicine I have tried for gastroparesis is Domperidone. The FDA doesn't approve of it. Many/most GI doctors do. Try to get a prescription from a GI doctor and you can then purchase the product in Canada. You cant get it at some compounding pharmacies in some states in the US, but the prices are 3 times the Canadian prices. Good luck! Buying from Canada can be done very easily online'