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testing????????

I was wondering is 13 week HIV antibody test considered conclusive for all HIV exposures?
I have read that heath care workers test out to 6 months after an exposure. Does it take longer for antibodies to build up after a needle *****? Are the test still accurate at 6 weeks and 13 weeks in a needle *****, and the 6 month test is just precaution?
Have you ever known of a person that tested neg at 8 or 13 weeks after needle ***** then test positive?

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239123 tn?1267647614
MEDICAL PROFESSIONAL
An HIV antibody test at 13 weeks is conclusive, regardless of the route of exposure.  If you had a negative result, you are home free.  No, I have never had a patient negative at either 2 months or 3 months and positive later.

Good luck--  HHH, MD
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239123 tn?1267647614
MEDICAL PROFESSIONAL
You're spitting hairs.  You can't find information on 12 vs 13 weeks because such data don't exist.  Thirteen weeks is quoted because it's equivalent to 3 months.  But some people consider 12 weeks the same as three months.   Nobody ever will know whether there is a measurable differnece between test reliability at 12 vs 13 weeks, because it isn't important enough for anybody to research it.

HHH, MD
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Avatar universal
The CDC purposely needs to state a maximum of 6 months for a reason. (If in doubt you may contact them @ 1-800-342-AIDS).  

The reason that they need to state 6 months is because they need to cover EVERYONE in the United States (and affiliated provinces/territories/etc.)
Remember, they need to cover EVERYONE, this means that most minute person in the country...even the one person out of millions that seroconverts @ 6 months or possibly later (mostly due to some other condition that caused their delay in seroconversion: e.g.: another immune disorder such as lupus or JRA, cancer, bone marrow transplant, etc.)  These persons are EXTREMELY RARE!!!!  

Since the onset of HIV/AIDS in the early 80's...HIV testing has come a LONG way.
Back then it was 6 months...now...99% of infected individuals can be accurately diagnosed with HIV by 6- 8 weeks. The latest being 3 months...unless your physical health was already jeopardized (as I stated above) by a pre-existing medical condition that affects your immune system.

The chance you fit this scenario is as much as me waking up as a woman tomorrow and driving to work in a Mercedes.  (just an added joke   :)  )


Your fine. PLEASE let it go.
Brian
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Avatar universal

Scared,

I am sorry you are worried still about HIV. A needle stick! That must have been horrible. I've done a fair amount of reading on the subject, here and elsewhere, and everything I've read indicates you are good to go! That's the good news.

It seems to me your task right now is not to determine how and when to get tested again. You're real task is accepting the fact that you are not infected with HIV. Your tests appear to be conclusive. Now, you just need to accept that fact. Concentrate on that, not testing.

Believe me, I know how hard that can be. You've lived with the fear for 3 long months (I think, based on what you've written). As much as you believe that you just want this all to be over, it can be hard to let go of something you've held on to for that long, no matter how unpleasant. Ever heard the old saying that if you do something for 21 days it becomes ingrained habit? I believe that. And I also believe that anxiety and fear, especially those who are predisposed to them naturally, can become a habit that is as hard to break as any other bad habit. And that, in your case, is what it is: a bad habit.

You are quite lucky, you know. There are plenty of people who post and lurk on this forum who are sweating out the months, weeks or days until they can take a 12 week HIV test to end (hopefully) their worries. You have all the assurance you need in the form of your conclusive negative HIV test. Now, take it and try to get on with your life. Easier said than done, I know. If you can't seem to do it on your own, consider speaking to a therapist. Therapy can help you distinguish between valid and irrational fears. And the idea that you still may have HIV is not a valid fear.

I'll end this by saying congratulations! You're in the clear!
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Avatar universal
That could be related to them often taking PEP after the exposure. Or maybe it is just the old standard 6 month that has not been updated. I am not sure.
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Avatar universal
A risk is a risk...as far as I am concerned. Whether it be sexual or needle stick injury.
I think it comes from the liability of the medical field/medical facility to have the person who was exposed to a needle stick injury to test @ 6 months...since they more than likely stick to the "old standard" for legal reasons.

Testing @ 13 weeks would be conclusive considered you do not have: Junior Rheumatoid Arthritis, onset of diabetes, Lupus, blood transfusion, or any other medical condition that has impacted your immune system recently.

A test for a "normal" (and I use that term loosely) individual would have known their positive result @ 6- 8 weeks.

I believe health care workers still "stick" to the old CDC standard since 1985, which is 6 months.  Any "normal" human being would know by 6 weeks as far as I am concerned.

I remember several years ago being tested (and this was in 1998), the woman who had tested me said: "Put it this way, if you were infected with the flu (a virus) , would it really take 3 months to create antibodies to it?"  Answer: No.
I thought this was a great analogy....or isn't it?

Brian
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Avatar universal
One more question, is it 12 or 13 weeks that is considered conclusive?
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Avatar universal
12 weeks is conisdered "conclusive" in New York State and I believe all of Canada.

Brian
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Avatar universal
Thank you Dr. Hunter.

I went to the CDC
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Avatar universal
I would kindly ask Dr HHH to comment on what has been posted by Brian123 regarding diabetes.

I have a mildly elevated fasting glucose level (technically diabetic but just above the norm and not talking any drugs). i have tested at 13.6 weeks and was thrilled that i can put the HIV story behind me and now I am reading (I should stop reading the internet) that diabetes may affect the conclusiveness of my results. This is the first time I hear about it - my doctor said my glucose level problem i irrelevant for HIV testing. up to 2% of population is affected by diabetes and probably the second half does not know about - is it possible that this can invalidate the modern HIV tests? hard to believe.

Dr HHH, I beg you, could you please comment on this issue. I am very worried now! Brian123, where do you have this information from?
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79258 tn?1190630410
I've never heard of diabetes affecting HIV testing accuracy, so I'm positive it doesn't have an effect. Considering that over 20 million people have diabetes in this country, I guarantee you that if it did affect testing accuracy, you'd hear about it all over the place.
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Avatar universal
yup - this is was my reasoning too - funny that I am just trying to believe in my fabulous result at 3 months and then I see something like this on the net and it freaks me out completely! thanks monkeyflower!
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Avatar universal
Please let me know
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79258 tn?1190630410
Your vaccination will NOT interfere with your test results.

If you don't mind my asking, what was the precipitating event? You're probably way overtesting...
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Avatar universal
You had misinterpreted my information for starters.

It is believed that someone who has just been recently diagnosed with diabetes I/II and does not have their diabetes under control and/or has had problems with diabetes that is "out of control" could have caused problems in seroconversion delay.

I think you are obsessing just a tad too much.
Stop reading so much negative info. on the Internet...it only will help perpetuate a fear that is non-existant to begin with in the first place.

Brian
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Avatar universal
It's too bad there are so many conflicting indicators out there about the testing window!

Just to add my two cents, since I did very extensive research on this last summer and the year following.

--Dr Handfield's view of the testing window is one of the shortest, citing 6 weeks as a reliable window barring any aggravated risks. That view is shared by massachusetts, I believe. But it is not a common view; very few experts will endorse it.

--The 12 week/13 week difference is confusing but mostly deals with finding a number of days that people can easily count. Most calendar months are not 28 days, so 3 months in the calendar sense is 13 weeks, but 3 months in the sense of one month equaling four weeks, makes for 12 weeks.

--The vast majority of medical opinions seem to agree on the 12-13 week range, including the states with the heaviest HIV case loads like New York and California.

--Nonetheless, the 6-month testing window is not such an outlandish professional opinion as it may appear in some of the discussion above. Lots of leading research centers, like Harvard University's health website, still say 6 months is the window. My PCP in New York has years of experience with HIV and still uses the 6 month window, largely because he _has_ seen people, even with the most recent tests, who tested positive in the 4-5 month range, even without health aberrations. The cases are extremely rare -- for instance, in a clinic that probably administers thousands of HIV tests every year, my doctor has seen a handful of cases over a period of 17 years.

--The difficulty with the testing window seems to be anecdotal versus documented evidence. There are many HIV cases with transmission circumstances that can't be confirmed or are kept confidential, thereby never making it into the CDC's registry and never becoming part of the official statistics. Sometimes when people claim to have been infected with HIV from one harmless incident of oral sex, for example, the doctors doubt the truthfulness of the person, so his data is excluded from the data set. Similarly with the testing window, people who claim they haven't had any sex in the last 6 months and suddenly test positive sometimes have stories that don't add up. The result is that you have mixed signals from the CDC and other researchers -- based on what they've seen, they wish they could give a more hopeful picture, but based on what they know might have been excluded from the data, they show restraint and play it conservative.

--Having gone through a big HIV scare in 2005, and having gotten tested 16 times in my life so far, I know how stressful these things can be. But I think it's important to differentiate getting an HIV test from thinking that you have have HIV. It's important to have the peace of mind to know your chances are extremely slim that you have HIV if you test negative at 6 weeks, BUT still go and get tested at 3 months and 6 months. If for no other reason, going to get tested at 3 months and 6 months helps the HIV medical field track information better and it will help confirm with greater certainty what the testing window actually is.

J
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239123 tn?1267647614
MEDICAL PROFESSIONAL
In general I agree with JohnnyV's comments.  But to clarify (again) my stance on timing of HIV testing, suffers from too much nuance; it breaks a cardinal rule of health education, the KISS principle:  "Keep it simple, stupid".  So although I sigh with frustration at having to repeat my views so often, I understand the reasons for misunderstanding.

I AGREE WITH 3 MONTHS AS THE TIME FOR DEFINITIVE RESULTS OF THE STANDARD EIA (ELISA) ANTIBODY TESTS AND I ALWAYS HAVE.  However, the reliability of a given test result depends on the prior probability of infection, not only the time interval.  Almost all questions on this topic describe very low risk exposures (say 1 chance in a million, often even lower).  With a negative test that has 90% reliability, those odds drop to 1 in 10 million.  Any common sense analysis says that is low enough to be considered 100% reassurance against infection.  Testing at 6 weeks (and maybe 4 weeks, especially with Duo EIA/P24 testing)meets that 90% standard.

I always tell questioners that if this level of reassurance isn't enough, i.e. they remain nervous despite such low odds, they should also get tested at 3 months.

To whoever asked about diabetes, it does not affect the reliability of HIV testing.  And although the conditions cited by brian123 (JRA and others) might affect the test results, it's only theory, not proved fact; if they have that effect, it is rare.  And of course the conditions themselves are rare as well.

HHH, MD
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Avatar universal
Johnny V

My PCP in New York has years of experience with HIV and still uses the 6 month window, largely because he _has_ seen people, even with the most recent tests, who tested positive in the 4-5 month range, even without health aberrations.




Now its comments like THAT, that make it IMPOSSBLE for WW to accept the 13 week test.  If anyone is concerned about testing ect.  you should go on aidmeds.com  Its a GREAT site with EXPERTS who are HIV+;  these experts have been working closing and following stats CLOSELY!!  They only support the most up to date info on that site.  This site seems to VARY wayyyyy toooo much with the Dr.s thoughts.  A 13 week test is as GOOD AS GOLD!!!!!  Its safe to move on with your life.  The ONLY way it might not be conclusive is if you have had other unprotected acts since, or if you are on CHEMO, heavily into drugs; or you immune system is SEVERLY DAMAGED.  If any of that stuff was the case then you wont be sitting here typing away, or reading forums right now.  13 WEEKS= CONCLUSIVE!!!!  No if ands or butts about it!!!!!!!!!!!!
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239123 tn?1267647614
MEDICAL PROFESSIONAL
"My PCP in New York has years of experience with HIV and still uses the 6 month window, largely because he _has_ seen people, even with the most recent tests, who tested positive in the 4-5 month range, even without health aberrations."

I don't believe it.  Not that I distrust JohnnyV's provider's honesty, just that research in provider behavior and recall show that retrospective recollections of that sort are often unreliable.  Providers tend to greatly overestimate the frequency of atypical events and patients.  The data from controlled studies are very much more reliable than any single health care provider's memory.  And the research on time to seroconversion are pretty good.

But Camass certainly is right, that regardless of how valid the data, statements like that--and testimonials on various websites--are an important reason for skepticism about my perspective by frightened, anxious persons.

HHH, MD
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Avatar universal
The window period is about as clear to me as how long HIV "survives" outside the body.

Even in some otherwise healthy individuals, doesn
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Avatar universal
My apology for having caused so much dissention from my one thread.

Brian
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Avatar universal
I kind of said that in jest. I know how long HIV remains infectious outside the body is much more complicated than the window period. I agree with what Dr. H says on this forum. I actually think he does a little cya of his own, in that he really feels that closer to 99% of people will convert by 6 weeks.
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Avatar universal
Hey folks,

Just to clarify, my PCP recalled around a half dozen cases of late seroconversion, remembering perhaps two with the newer tests. He did tell me, however, that in all these cases, the people who tested positive had "flashing red lights" around them. They'd had sex with hundreds of partners with no protection, or they'd been sharing needles for 20 years, or they'd been with an HIV+ partner in a long-term relationship.

To clarify what he told me after my HIV scare last year, he said that after three months, I no longer needed to use protection with my wife and I could live my life as if I didn't have the virus. So it wasn't as if he pasted an orange warning sign on my chest and told me to live in fear for 6 months. On the contrary, he told me to relax and put my worries behind me...

BUT he insisted that I get tested at 6 months. He told me it was more like participating in ongoing research. He fundamentally trusts the 3-month window, but his trust isn't 100% so he won't take any chances on missing an infection.

I don't know what more to say to people who have such heightened stress about this testing window. All I can say is I lived for a long time with HIV risk constantly hovering over me, since I am bisexual and became active with both sexes in the late 1980s when a lot was not known. You just have to learn to live with these mental nuances. Getting an HIV test is not the same thing as thinking it's likely you have HIV. You could feasibly be screened for testicular cancer at the age of 25 and not assume for any reason that you have it; you're just going for a routine checkup. Think of it that way, and relax.

J
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Avatar universal

Perhaps we should be careful about offering medical advice. Perhaps we should not do so at all. Perhaps we should be wary of becoming like so many other sites out there, where "lay" people offer up their opinions on this topic. And then scare the **** out of the normal users who are anxious and afraid.

Personally, unless I can reassure someone, I won't offer my opinion on anything. The people who come here pay to see the Doc, not me.

Just a thought.
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