Combo treatment : Baraclude + Viread

[nayana_]

What is the dosage combination for both drugs?

[phihungmd]

Indications and combinations tried current for various HBV populations.

For HBeAg-positive chronic HBV:

Interferon + lamivudine
Interferon + telbivudine
Interferon + ribavirin
Interferon + thymosin
Lamivudine + adefovir
Lamivudine + telbivudine
Lamivudine + thymosin
Lamivudine + HBV vaccine
Tenofovir + emtricitabine
Adefovir + emtricitabine
Clevudine + emtricitabine
Adefovir + bicyclol
Thymosin + bicyclol

For HBeAg-negative chronic HBV :

Interferon + lamivudine
Interferon + adefovir
Interferon + ribavirin
Clevudine + emtricitabine
Lamivudine + HBV vaccine

For HBV and HIV coinfection :

Interferon + adefovir
Tenofovir + lamivudine
Tenofovir + emtricitabine
Lamivudine + entecavir

For HBV and hepatitis C coinfection:

Interferon + ribavirin
Interferon + lamivudine

For Interferon non-responders:

Interferon + lamivudine
Interferon + GM-CSF
Interferon + HBV vaccine

For Lamivudine-resistant HBV:

Peginterferon + adefovir
Adefovir + lamivudine
Adefovir + entecavir (case reports)
Adefovir + tenofovir (case reports)
Tenofovir + lamivudine (case reports)

For Adefovir non-responders:

Adefovir + lamivudine
Tenofovir + lamivudine
Tenofovir + emtricitabine

For Pediatric population:

Lamivudine + interferon-α

For Acute HBV infection:

Adefovir + lamivudine

For Severe HBV reactivation:

Nucleosides + steroids

For Asymptomatic chronic carriers:

Lamivudine + HBV vaccine

Prevent recurrence after liver transplantation in HBV-positive recipients:

Lamivudine + HBIG
Adefovir + HBIG
Entecavir + HBIG
Lamivudine + adefovir

Prevent recurrence after liver transplantation with HBcAb-positive donor:

Lamivudine + HBIG

[phihungmd]

Until now, I did not see guide for naive patients chronic hepatitis B treated with entecavir plus tenofovir.
I just know that if patients are resistant to adefovir may be replaced by teonofovir combined with entecavir under the guidance of EASL.