Aa
Confusing Hept B Test Results
Could you please interpret my lab results for HBV?
Ag HBs: pozitiv
Anti - HBs: < 2 UI/L
Anti - HBc: pozitiv
Ag HBe: negativ
Anti - Hbe: pozitiv
Ig E: 220.7(Possibly due to pollen allergy?)
Direct bilirubin: 0.37
Indirect bilirubin: 0.97
Total bilirubin: 1.34
ALAT/GPT/ALT: 39
ASAT/GOT/AST: 30
I'm confused since the Ag HBs is positive and Anti - HBs is also positive, though in a low quantity. Could this be the start of a seroconversion?
Ag HBs: pozitiv
Anti - HBs: < 2 UI/L
Anti - HBc: pozitiv
Ag HBe: negativ
Anti - Hbe: pozitiv
Ig E: 220.7(Possibly due to pollen allergy?)
Direct bilirubin: 0.37
Indirect bilirubin: 0.97
Total bilirubin: 1.34
ALAT/GPT/ALT: 39
ASAT/GOT/AST: 30
I'm confused since the Ag HBs is positive and Anti - HBs is also positive, though in a low quantity. Could this be the start of a seroconversion?
HBV DNA came back and the count is 2000 IU/mL (11,660 copies/mL) from 2210 IU/mL (12,338 copies/mL) a year ago.
--For 1 year, the change was not considered significant.
--For 1 year, the change was not considered significant.
Ok,my HBV DNA came back and the count is 2000 IU/mL (11,660 copies/mL) from 2210 IU/mL (12,338 copies/mL) a year ago.
I do have to tell you that I was on a alternative treatment for the last year. I've not followed it rigorously because I was not a that much of a believer in alternative medicine.
However, I'll embark on the same treatment consisting in the following and I'll get tested every 4 months to see the exactly the evolution.
Organic Selenium 200MCG . It is important to use an organic form of the mineral like selenomethionine rather other forms.
- I used it everyday
Organic Liquid Vitamin E. Avoid dl-alpha-tocopherol, the synthetic form.Natural Vitamin E is called d-alpha tocopherol. The synthetic form of Vitamin E is dl-alpha tocopherol.
-I used it about for 5 months out of 12
Tincture of : Milk Thistle, Astragalus and Schizandria .
-I used these for about 5 months out of 12.
I also consider flying over to Japan and get a treatment with SNMC (Stronger Neo-Minophagen C). This drug is made of the natural occurring Glycyrrhizin . Th studies show that is far more effective in interconversion than interferon and with less side effects.The drug is not used in US.
I do have to tell you that I was on a alternative treatment for the last year. I've not followed it rigorously because I was not a that much of a believer in alternative medicine.
However, I'll embark on the same treatment consisting in the following and I'll get tested every 4 months to see the exactly the evolution.
Organic Selenium 200MCG . It is important to use an organic form of the mineral like selenomethionine rather other forms.
- I used it everyday
Organic Liquid Vitamin E. Avoid dl-alpha-tocopherol, the synthetic form.Natural Vitamin E is called d-alpha tocopherol. The synthetic form of Vitamin E is dl-alpha tocopherol.
-I used it about for 5 months out of 12
Tincture of : Milk Thistle, Astragalus and Schizandria .
-I used these for about 5 months out of 12.
I also consider flying over to Japan and get a treatment with SNMC (Stronger Neo-Minophagen C). This drug is made of the natural occurring Glycyrrhizin . Th studies show that is far more effective in interconversion than interferon and with less side effects.The drug is not used in US.
what type of harm will stopping taking meds do to my liver ?
--The possibility of flares.
--The possibility of flares.
yes you remember my readings correctly.
cajim: "and maybe you by western plus some. "
well, coming from a middle eastern back ground, this disease is , like in the chinese culture, has been given some attention with non drug methods of treatment.. they do not involve any type of supliments..no over the counter vitamins..
there is one method of clearning many illness and diseases that involves what is called " black seed " or as translated from arabic " the blessed seed" .
the black seed has been used for thousands of years to cure 100's of diseases.. in the muslem culture it is said to " have a cure for everything except getting old and/or dying"
i will translate the part where it discusses liver diseases and list it on here for anyone that wants to try..
i did try it ofcourse but i started after having started my meds so i am not sure which one is doing a better job though if i clear my hbv on my own one day, i will most likely give it to the blessed seed.
will start natural treatment methods in a seperate thread .
still though cajim, i understand everything you said in your reply and i am aware of it all... my question was in my own case or someone else's case that is similar ( i know someone else on here that has exactly the same initial readings as mine ), what type of harm will stopping taking meds do to my liver ? and no i am not planning on quitting my meds..all hypethical
cajim: "and maybe you by western plus some. "
well, coming from a middle eastern back ground, this disease is , like in the chinese culture, has been given some attention with non drug methods of treatment.. they do not involve any type of supliments..no over the counter vitamins..
there is one method of clearning many illness and diseases that involves what is called " black seed " or as translated from arabic " the blessed seed" .
the black seed has been used for thousands of years to cure 100's of diseases.. in the muslem culture it is said to " have a cure for everything except getting old and/or dying"
i will translate the part where it discusses liver diseases and list it on here for anyone that wants to try..
i did try it ofcourse but i started after having started my meds so i am not sure which one is doing a better job though if i clear my hbv on my own one day, i will most likely give it to the blessed seed.
will start natural treatment methods in a seperate thread .
still though cajim, i understand everything you said in your reply and i am aware of it all... my question was in my own case or someone else's case that is similar ( i know someone else on here that has exactly the same initial readings as mine ), what type of harm will stopping taking meds do to my liver ? and no i am not planning on quitting my meds..all hypethical
"how much flare up/negativity/damage to my liver might i suffer should i ever " hypethically" quit my meds ? any idea.. ?"
If I remember right, you were HBeAg(-) HBeAB(+) ALT/AST normal at the start of treatment. If so, you were right 2007 guideline would have recommended monitoring rather than treatment. For patients with HBeAg(+) HBeAB(-) they have a point of stop 1 to 2 years after they have reached HBeAg(-) HBeAB(+). For you the stoppoint is not clear cut, but there is one: when you become HBsAg(-) HBsAB(+)! Even though hard, this stoppoint is worth fighting for. Why?
1. Normal ALT/AST UND HBV-DNA cannot be goals of treatment anyway. Many patients with normal ALT/AST UND HBV-DNA by antiviral drugs or IFN progress anyway, some examples follow:
zsi020802: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 31, AST 70, cirrhosis.
sk021014: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 24, AST 23, HBV-DNA (-), cirrhosis, fibrosis.
bmbx021016: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT/AST normal, HBV-DNA UND, fibrosis G3S4.
fyheting021118: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 25, AST 25, HBV-DNA UND, cirrhosis.
liq1218021111: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 48, AST normal, HBV-DNA UND, cirrhosis.
2. Though low, there are a very small percentage of patients that achieve HBsAg(-) HBsAB(+) by antiviral drugs/IFN.
3. Your helping your liver achieve HBsAg(-) HBsAB(+) only helps your antiviral drug, no conflict there.
How? In my personal opinion, western drugs are chemicals that are toxic to a greater or lesser degree to our body and give our liver the burden of detoxification. By giving your body plenty of nutrition, avoiding as much toxins by mouth as possible and helping your body detoxify as much as possible, you may cancel out the toxicity from the antiviral drug, only receive its benefit and further go on to adjust your body environment that becomes less and less appropriate for the survival of HBV.
Willy-nilly we are all guinea pigs for fellow patients that are to come, me by non-western treatment, steven by combo western treatment, zellyf by monitoring, and maybe you by western plus some. Years from now, fellow patients may know what to choose better than us.
If I remember right, you were HBeAg(-) HBeAB(+) ALT/AST normal at the start of treatment. If so, you were right 2007 guideline would have recommended monitoring rather than treatment. For patients with HBeAg(+) HBeAB(-) they have a point of stop 1 to 2 years after they have reached HBeAg(-) HBeAB(+). For you the stoppoint is not clear cut, but there is one: when you become HBsAg(-) HBsAB(+)! Even though hard, this stoppoint is worth fighting for. Why?
1. Normal ALT/AST UND HBV-DNA cannot be goals of treatment anyway. Many patients with normal ALT/AST UND HBV-DNA by antiviral drugs or IFN progress anyway, some examples follow:
zsi020802: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 31, AST 70, cirrhosis.
sk021014: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 24, AST 23, HBV-DNA (-), cirrhosis, fibrosis.
bmbx021016: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT/AST normal, HBV-DNA UND, fibrosis G3S4.
fyheting021118: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 25, AST 25, HBV-DNA UND, cirrhosis.
liq1218021111: HBsAg(+) HBsAB(-) HBeAg(-) HBeAB(+) ALT 48, AST normal, HBV-DNA UND, cirrhosis.
2. Though low, there are a very small percentage of patients that achieve HBsAg(-) HBsAB(+) by antiviral drugs/IFN.
3. Your helping your liver achieve HBsAg(-) HBsAB(+) only helps your antiviral drug, no conflict there.
How? In my personal opinion, western drugs are chemicals that are toxic to a greater or lesser degree to our body and give our liver the burden of detoxification. By giving your body plenty of nutrition, avoiding as much toxins by mouth as possible and helping your body detoxify as much as possible, you may cancel out the toxicity from the antiviral drug, only receive its benefit and further go on to adjust your body environment that becomes less and less appropriate for the survival of HBV.
Willy-nilly we are all guinea pigs for fellow patients that are to come, me by non-western treatment, steven by combo western treatment, zellyf by monitoring, and maybe you by western plus some. Years from now, fellow patients may know what to choose better than us.
NOT TRYING TO "HIJACK" THIS THREAD.. IT IS A NO NO as we all know but its kinda related.
hmmmm.. i just noticed something...kinda funny .. actually it is NOT funny at all..
my initial count was 3470 copies and on that i decided to go for treatment. thought this over over the 2000 "copy" limit..well obviously i didnt pay much attention the different measurements and that i didnt have 2000 ul/ml but rather a littl less than 500 ul/ml which required monitoring nstead of treatment.
how much flare up/negativity/damage to my liver might i suffer should i ever " hypethically" quit my meds ? any idea.. ?
maybe the poster of this thread might also benefit from cajim's answer
hmmmm.. i just noticed something...kinda funny .. actually it is NOT funny at all..
my initial count was 3470 copies and on that i decided to go for treatment. thought this over over the 2000 "copy" limit..well obviously i didnt pay much attention the different measurements and that i didnt have 2000 ul/ml but rather a littl less than 500 ul/ml which required monitoring nstead of treatment.
how much flare up/negativity/damage to my liver might i suffer should i ever " hypethically" quit my meds ? any idea.. ?
maybe the poster of this thread might also benefit from cajim's answer
2007 Guideline:
HBeAg-negative, anti-HBe Positive Patients with Normal ALT Levels and HBV DNA <2,000IU/ml (Inactive HBsAg Carriers). These patients should be monitored with ALT determination every 3 months during the first year to verify that they are truly in the “inactive carrier state” and then every 6-12 months. If the ALT level is subsequently found to be elevated, more frequent monitoring is needed.
HBeAg-negative, anti-HBe Positive Patients with Normal ALT Levels and HBV DNA <2,000IU/ml (Inactive HBsAg Carriers). These patients should be monitored with ALT determination every 3 months during the first year to verify that they are truly in the “inactive carrier state” and then every 6-12 months. If the ALT level is subsequently found to be elevated, more frequent monitoring is needed.
for an E antigen negative, i believe the count was a big high. if i am correct and i think cajim has the right info on the 2007 guide, treatment is recommended for hbeag negative with a count of over 2000 copies.
cajim, please correct me if i am wrong
bob209, let us know what your dna count is this time around.. maybe you're down to UND. also be ware that if you start treatment with this higher than you should count while e antigen negative, you are going to be taking meds indefintely. ( i,e.. for life ) ..
cajim, please correct me if i am wrong
bob209, let us know what your dna count is this time around.. maybe you're down to UND. also be ware that if you start treatment with this higher than you should count while e antigen negative, you are going to be taking meds indefintely. ( i,e.. for life ) ..
Thank you all for your comments.
I'm still wainting for the HBV DNA count. Probably I'll have it in a few days.
However, a year ago the count was 2210 IU/mL (12,338 copies/mL).
I'm still wainting for the HBV DNA count. Probably I'll have it in a few days.
However, a year ago the count was 2210 IU/mL (12,338 copies/mL).
seroconversion from what to what ?
you seem to have seroconverted from hbeag postive to negative and thats good. you do need to know your DNA count so that you can be led to the proper direction.
if you mean seroconversion from hbsag pos to negative, the number stated on the right of hbsab isnt irrelevant as far as i know since it is standard to put this number that corresponds to the minimum needed to show any type of antibody . in your case it is < 2 UI/L and you obviously have less than that.
good luck .
ps: u do need a viral load count so you know where you stand with this virus count in your body
you seem to have seroconverted from hbeag postive to negative and thats good. you do need to know your DNA count so that you can be led to the proper direction.
if you mean seroconversion from hbsag pos to negative, the number stated on the right of hbsab isnt irrelevant as far as i know since it is standard to put this number that corresponds to the minimum needed to show any type of antibody . in your case it is < 2 UI/L and you obviously have less than that.
good luck .
ps: u do need a viral load count so you know where you stand with this virus count in your body
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