Entecavir Dosage and Resistance

[hepbcurepls]

I was wondering what is the difference between 0.5 mg and 1mg in regards to resistance. Will 0.5 mg of entecavir cause resistance in patients who never have been on any nucs and no polymerase resistance detected vs 1mg. My doctor wants me to take 1mg vs 0.5 mg but I have been been on any nucs and show no resistance to any nucs during genotype testing. These are the test results

Polymerase Inhibitors
3TC (lamivudine or Epivir) NO
LDT (telbivudine or Tyzeka) NO
FCV (famciclovir or Famvir) NO
ADV (adefovir or Hepsera) NO
ETV (entecavir or Baraclude) NO
_______________________________________________________

Precore and BCP Mutations
_______________________________________________________
Precore (TAG) G1896A
BCP A1762T,G1764A
_____________________________________________________
OTHER MUTATIONS DETECTED:
POLYMERASE: Not Detected
PRECORE: C1858T
BCP: Not Detected

Am I ok to take 0.5 mg instead of 1mg? I have read that 1mg is only for resistance.

[Royal36]

I am on this 0.5mg nuc's since January 2015 so far so good i can't complain at all and i know another member who is taking this medication since 2009 he still doesn't have any issue with the antiviral therapy and will hear from him more if there is any.

[hepbcurepls]

that is what i heard, but even with all those mutations is 0.5mg still the recommended dose?

[hepbcurepls]

I have some kidney damage egfr at 72. I was going to go TDF but worry doctor worried about kidneys

[Ibro982003]

Usually they start with 0.5mg if you have never been on any nuc's.

[stef2011]

why etv since tdf is more potent, zero resistance, cheaper?