Aa
Aa
A
A
A
Close
Avatar universal

Finally got the first "full picture" of my results... Should I start treatment?

ast 18 (ref range: 10-30 u/l)
alt 19 (ref range: 6-29 u/l)
vit d, 25-oh, total: 28 (ref range: 30-100 ng/ml)
pth intact 35 (ref range: 14-64 pg/ml)
hbsag positive
hbsab negative
hbcab positive
hbeag negative
hbeab positive
hbv dna 1311 ui/ml
hbsag count ??? ui/ml (can't do the test in the US, but I'm guessing it's going to be more than hbv dna?)
alpha fetoprotein tumor marker 2.0 (ref range: <6.1 ng/ml)
liver fibrotest score: 0.29 (F1) minimal fibrosis
acti test (assesses activity (inflammation in chb)): score 0.05 (A0) no activity.
hep a ab negative (should I get vaccinated?)
hep d co-infection negative
Ultrasound: No significant abnormality is identified.
tests pending: hbv genotype

What do you think guys am I a good candidate to start treatment? If so, what treatment plan would you advise? Is peg-Intf an option? How likely will my fibrosis progress to F2? What phase do I belong to (e.g. immunte tolrent, clearance, inactive, etc)? How often should I monitor myself? Also, would it be beneficial to get a FibroScan in addition to the FibroTest I already got?

I'm going to discuss with my gi about my treatment options this Tuesday, and also going to have a second opinion appt with a hepatologist specialist next month. I would also appreciate if you could recommend good docs in LA area.

Thanks for your help!

Best Answer
Avatar universal
doctors .... 10 or more years ago one doctor told me that I'm non-infectionous and I'm ok with my hbv, he even didn't told me that I have to monitor this, because 10 years ago they believed that HBe-, HBeAb+ and undetectable dna (10 years ago und dna was probably < 200 or 500) is very good outcome. Now we know it's bulshit.
So remember that not all doctors are up to date and also they don't want to take responsibilty about any actions out of official regulations.
Bringing PTH to minimum is not your target it's just signal that you have obtained your max safe vit d level when vit D has the best immunoregulation effect.
42 Responses
Sort by: Helpful Oldest Newest
Avatar universal
http://www.vitamindwiki.com/Vitamin+D+toxicity+after+50,000+IU+daily+for+2+years+(no+surprise)+%E2%80%93+April+2015

Vitamin D toxicity after 50,000 IU daily for 2 years (no surprise) – April 2015
Helpful - 0
Avatar universal
i myself take 4.600.000iu of vit d3 per month, 150.000iu daily since 2 years and many others here take since long time and how can it make damage with the monitoring?



Helpful - 0
Avatar universal
https://www.researchgate.net/profile/Salvatore_Minisola/publication/221759661_Guidelines_on_prevention_and_treatment_of_vitamin_D_deficiency/links/0deec52cacdc1ef7a9000000.pdf

and 1million iu is not for sick patients but only for deficient patients
Helpful - 0
Avatar universal
10.000iu of vit d is not a high dose, all hbvers must take vit d and must not have deficiency to stay healthy this is what we know for a fact.what is not proven is vit d to make damage there are only a few clinical cases taking millions of iu daily for over 6months and even in these few clinical cases there were no permanent damage.

italian guidelines for vitamin d deficiency prescribe 1million iu

http://www.vitamindwiki.com/How+often+might+50000+IU+vitamin+D+be+taken+-+results+of+clinical+trials

http://www.vitamindwiki.com/Vitamin+D+-+Facts+and+Myths

this said, dont take any vitamin d it is your choice
Helpful - 0
Avatar universal
Royal36, this study that Stephen quoted dosent prove that vitamin d helps fibrosis.
It only shows associative relationship with hbv, but it's not proven that it's the cause to hbv or that taking it helps to clear the virus. There is not one study that proves that, only show associative relathship. You might as well take other supplements that have associative relathionship, dosent mean anything...

If I were you I would be more worried about the damage a big dose of vitamin (10,000iu) can cause to your kidneys.
Helpful - 0
Avatar universal
Thanks Stephen and stif, i do take 10,000iu of vit D3 daily though, i just want to make sure how it really affects the fibrosis.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis B Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.