Good classical hepatologist presentation of HBV antiviral resistance management

[Hepatitis Researcher]

The following link will give access to a nice presentation that reflects a leading classical hepatologists view of HBV antiviral resistance issues and management.

It is still too conservative in my view and is , as a mainstream presentation - invisibly guided by the need to preserve money in treatment approaches - not by the presenter - but by the whole, still mainly monotherapy oriented start approach. The reason for the preference of this approach is rarely cited - combos cost too much ( the major reason by far)  and hold issues of potential toxicity and have not been tested in large trials and are not typically effective in further suppression of viral loads compared with mono therapies. But they have the dramatic advantage to cross-protect either drug in the combo from resistance development. This advantage overrules the above problems and prevents playing chances for resistance development that might not be manageable in quite a few patients in the long term. There is an obvious shyness to express these views even by experts who do know or strongly suspect this forthcoming issues.
This comment is in itself an oversimplified view, of course. Each patient has individual considerations in an optimized approach - HBV is a very complex disease and is actually a dozens of diseases.

Here is the link I hope it works

http://clinicaloptions.com/Hepatitis/Treatment%20Updates/HBV%20On%20Treatment/Virtual%20Presentation/Presentation/Pages/Page1.aspx

[stevenNYer]

Just finished the presentation.  Thanks for the referral to important info.  Always learn something new.

It makes me feel great that I am already being more proactive instead of waiting for virologic breakthrough.

I hope others see this thread and follow the presentation.

Now, about that CME credit ;)

[zellyf]

I was able to read this last week...I'm so glad to see HR's comments on the continued urging of a monotherapy approach because I was very confused by conflicting information about that.

The link was broken for me so for others who may have the same problem you may have to cut and paste this in parts or type it in manually:

http://clinicaloptions.com/Hepatitis/Treatment%20Updates/HBV%20On%20Treatment
/Virtual%20Presentation/Presentation/Pages/Page1.aspx

[cajim]

I am not too good with computers.  I tried HR's link but could not find the presentation.  Would be very grateful if Steven or zellyf could post their link that allowed them to read the presentation.  Many thanks.

[Hepatitis Researcher]

Just highlight zellyfs webpagelines together in one highlight. Then hold down the control key and type the letter c. Then go to the browser line and click there. Then hold  again the control key and type the letter v (while holding down the control key) Now hit enter..

[stevenNYer]

Both HR and Zelly already gave the link.  Copy and paste it to your browser's address entry.

It will take you to the clinical options login page.  Just sign up as a new member and you're in.

[Ann8]

Zellyf & CAJim,

How do you hug & kiss your kids? Since diagnosed, I have this fear of hugging my kids, my heart was bleeding as my kids like to hug & kiss me before the bed time.......

p/s : they all have 3 jab of vacc since born & due to check for antibody soon.

[zellyf]

Ann8, I posted to your other thread re: this topic.  

cajim, send me a note if you continue to have problems.