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9674600 tn?1405211066

HBV and HDV infection

Dears,

thank you for always help my health. last week i tested my HDV. please find attached picture showed my test result. HDV is very high. ALT/AST is very high. HBV is normal .... my doctor said: now asap start Peginterferon + tenofovir. last month i changed Entecavir to Tenofovir. now i using for alone tenofovir. but china doctor said: if your ALT/AST high then dont start peginterferon + tenofovir. what should i do? i'm afraid for this result.
3 Responses
Avatar universal
Your HBsAg quantitive is so low. Is it becasue HDV coinfection that HDV suppress HBsAg release or it's not related ?
With such low HBsAg and high ALT you have great chance to clear HBs on peginf but your advanced fibrosis may be a problem. Not sure if you need tenofovir if your hbv dna is close to undetectable now.
Also why both HBe and antiHBe are negative ? I thought one is always positive for chronic carriers ? Also anti-HBc is always possitive in chronic carriers too. So your tests look very uncommon.
Maybe some more experienced users can comment this, theres many questions here.
9674600 tn?1405211066
thank you. my last result 2015.07.15.
HBsAg - 79.73
Anti-HBs <2
HBeAg 0.935
Anti-HBe - 1.39
Anti-HBc - 0.006
PreS1Ag - 0.021
PreS1Ab - 0.023
ALT - 372.4
AST - 155.0
HDV - 11831083copies/ml, 3479731IU/ml
HBV - 30copies/ml, 9IU/ml.

my HBsAg is low. i think HBsAg is related for HDV. why my HDV not related for HBsAg?
Avatar universal
Of course HDV can not exist without HBV.
It's important if your HBsAg is quantitive result ? If yes, it's very good result but not sure also if advanced fibrosis doesn't mess something here.
Let's wait for other comments.
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