HBeAg non-reactive to reactive

[kinetix1208]

Hi Everybody,

My latest results indicates that my HBeAg turns out to be reactive again. Is this really possible? I don't know if there is an HBeAg mutation that exist. What does this result implicates? Please advise.

12/17/2011 Results: (latest)
Anti-HBs (CMIA)      -  0.00           mIU/ml      non-reactive
HBsAg (CMIA)         -  2145.34                       reactive
Anti-HBe (CMIA)      -  0.66                             reactive
HBeAg (CMIA)         -  29.17                           reactive
SGPT                       -  416.79

8/27/2011 Results:
Anti-HBs (CMIA)      -  0.00           mIU/ml      non-reactive
HBsAg (CMIA)         -  2518.79                       reactive
Anti-HBe (CMIA)      -  0.56                             reactive
HBeAg (CMIA)         -  0.559                           non-reactive
SGPT                       -  37.09

My HBsAg decreases and SGPT exponentially increases, does this mean that there is a response in my immune system with the virus?

[jhon83]

Hi, I have a HBeAg reactive, my result is 199.1, ref.value is 1, what should I do to have a HBeAg non-reactive. ty

[kinetix1208]

Any comment on the above post?

[kinetix1208]

Below are my latest results:

12/17/2011 Results:                                                                  COV
Anti-HBs (CMIA)      -  0.00           mIU/ml      non-reactive        10.0
HBsAg (CMIA)         -  2145.34                       reactive                1.0
Anti-HBe (CMIA)      -  0.66                             reactive                1.0
HBeAg (CMIA)         -  29.17                           reactive                1.0
SGPT                       -  416.79          U/L                                  10 - 41

1/16/2012 Results:                                                                    COV
Anti-HBs (CMIA)      -  0.00           mIU/ml      non-reactive         10.0
HBsAg (CMIA)         -  1976.07                       reactive                  1.0
Anti-HBe (CMIA)      -  2.01                             non-reactive           1.0
HBeAg (CMIA)         -  69.95                           reactive                  1.0
SGPT                       -  305.51          U/L                                   10 - 41
Anti-HBc IgM            -  0.74                            non-reactive            1.0
Anti-HBc Total          - 13.88                           reactive                   1.0

Remarks: Anti-HBe count below cut-off value is considered reactive.
Specimen - Slightly icteric sample

HBsAg and SGPT went down a little bit, HBeAg went up. I'm a bit confused with the Anti-HBe results since the remarks says that it is now non-reactive. I'll confirm this tomorrow in the laboratory.

Is this possible? Anti-HBe goes from reactive to non-reactive?

Also, it says that the specimen is slightly icteric. Am i getting into the state of jaundice?

Is my situation worsening?

[HOTH]

Thanks for getting back to me, Kinetix. Your response is very very helpful.  Your response only confirms that I need to get a better understanding of the information I'm taking in.  I thought that normally all adults clear HBV with no damage unless they 1) got it as a child  2) received an infected blood transfusion 3) had a suppressed immune systems do to medical drugs or HIV.  The lifestyle you described is the lifestyle of the average American.  

I believe the static I read said that 90% of people clear HBV without having any symptoms whatsoever.  I now see that that 10% should also include people outside of the criteria I mentioned.  

Thanks again,
HOTH

[kinetix1208]

No blood transfusion and i didn't take any drugs as i remember. I think it's because when i had this disease i was at my non-healthy lifestyle, and so it gets chronic. I barely ate fruits that time, no exercise, don't get enough sleep, i ate food at fast food restaurants always (no nutrition), no vitamin intake. And that i guess how it becomes chronic, too late when i have noticed it.

[HOTH]

kinetix, you said that as far as you know, you did not have HBV from birth and that you last gave blood in 2004 with no issue.  Have you had a blood transfusion or been on drugs to suppress your immune system for medical or non medical reasons?

If those questions are to personal,  please forgive me.  I do not mean to offend.  I only ask because I'm trying to get my head around all of the info. I'm learning about how one gets chronic hbv.

Thanks in advance,
HOTH

[kinetix1208]

No, i'm not a carrier since birth, the last time i donated a clean blood was 2004 as i recall. I found out that i have these disease in 2008, it was already at chronic stage, too late. I have not been in any kind of therapy, just a healthy living. I take a lot of vitamins everyday, vit d3 (6000 IU), c (1500mg), e (800 IU), etc. as posted here in the forum. It's the best thing I can do since i cannot afford any medication continuously. I'd like to try tenofovir as recommended by stef but I'll try to see it first if it fits with my budget.

[grmr]

@ kinetix

are you a carrier since birth? have you ever went through any therapy?

[kinetix1208]

Thanks stef for answering, it's really a great help especially in understanding the situation.And thanks for the recommendation, I'll try to find a doctor who would prescribe me with tenofovir. I read your post that tnf has low to zero sides and has no resistance.

[kinetix1208]

Please I need some helpful advise on this. Please do share your insights. What does it means being HBeAg non-reactive to reactive again.

[rusty999]

STop drinking alcohol if you value your life have a healthy life.... HBeAg:REACTIVE =infectious