Elevated WBC

[Magda123]

Hi! End of Jan 2013, i was still in the acute stage of hepa b. 13 April 2013 - IGM non reactive. I am still considered in acute stage? How is elevated WBC related to hepa b? Does this mean my immune system is fighting off the virus?

Hbsab neg
Hbeag neg
Hbeab pos
Viral load as of end Jan 2013 is 580iu/ml

[stef2011]

you may hae a slow response on hbsag, today we have hbsag quantification so they found many clear hbsag slowly by 12 months.the only way to know is 2 hbsag quant tests one month aprat so we can see how it is declining and understand when it will be cleared

hbcabigm can become neg after 6 months but you may still be clearing hbsag

[Magda123]

Stef, just a further need of clarification. If hbcab igm is was positive 3mos back, and is now negative. What does it mean? this will be negative after 6mos if chronic, right? In my case, do i still have the chance to clear within the next months? As i read and seen in a graph that hbsab will appear after 6mos from infection.

[Magda123]

Steff, how about shiitaki mushroom? Any idea?

[stef2011]

some mushroom are dangerous for the liver so it is best to avoid them in the diet unless you are very very very sure of the type of mushroom because some types are even beneficial and some boost intf production like maitake

[Magda123]

Stef, you've mentioned previously that mushroom is contraindicated or is bad for the liver.

[calebz]

If our HBsAg is high you may need treatment anyway - according to some new studies around the net having low HBV DNA does not mean no liver damage or low risk of HCC ( D genotype the HCC risk is the same despite low DNA)

And if its low then you should try Interferon to try and clear HBsAg totally.

Which doctor you go to ? I saw some presentation by a doctor in Paris - Creteil - looking at his presentation it looked that he is very updated maybe try that ?

[calebz]

The high ALT is correlated with your good results - it means fighting off the infected cells inside liver. It will go down after you clear HBsAg - which you are doing judging on your good results.

Please post back your results after you finish your 48 week treatment.

[GARBANZO]

Well I took some immune system booster this winter with probiotics.  It is called BION 3 but I don't even know if that's good quality staff or if it has had impact on my HBS ab creation. As well some vitamin c natural staff.  

[GARBANZO]

Hello. I am hbe ag -ve and hbe ab +.  I have not made HBSag quant.  Why?? becouse my doctor Told me it is useless in my case. He told me It is usefull if I go for treatement. With no fibrosis at all and viral load of 110 IU he told me there is no need to go for traitement right now....... he told me I WOULD have SIDES  and he prefer to watch it closely.  I trust my doctor I live in France and i've been told he is good one.

For me balanced diet is mediterranean food with olive oil,fruits,  lot's of salads, vegetables and never industrial things or bad meat industrially treated. Well anyway I have had very bad luck becoming cronically and my HBS ab = 3 UI r just not enought.  Better than nothing I suposse that means my Inmune System is working a little.

[mustthinkpositive]

No I did not take anything.  Just balance diet, proper exercice and positive thinking.

What is your balance diet? No supplements? Thx Garbanzo.

[Magda123]

What was your hbsag quant before and now? Are you hbeag -/+? at least you have developed antibodies. I think you just have to boost more your immune system. Do you have supplements?

[Magda123]

I am now making shiitaki soup every other day.

Steff, does it matter during acute stage if hbeag - and hbeab +? is this good or bad?

[fredz2013]

concerned about high ALT & AST...


taking sevibo for 1 yr then i decided to undergo pegintf.
stop taking sevibo for 1 month then started the mono pegintf.

before taking sevibo
HBV Viral load 640M copies/ML

after 1 yr of sevibo
HBV Viral load is 37 iu/ml

before pegintf:
HBsAg II Quantification 1,392 iu/ml
HBV Viral Load 37 iu ml

results- 24 weeks of  Pegintf
HBV Viral load is <6 iu/ml or 35 copies/ml
HBsAg II Quantification 314.90 iu/Ml

I understand the result is good.

what worries me is the consistent  high ALT
and SGOT result is high also (although test done once only after 24wks of pegintf)

ALT 64.60        (declining results)
SGPT 42.11    

i have mild fibrosis result before pegintf .
what will be the effect of consistent high alt in my liver?

[stef2011]

you may try Maitake Mushroom Extract which is known to increase your own interferon production, it also has betaglucans, if your hbsag is lower than 1000iu/ml and if the mushroom makes enough intf this will help you clear, if hbsag is high no way it can work because hbv is able to block intf effect and it does

[GARBANZO]

No I did not take anything.  Just balance diet, proper exercice and positive thinking.  I have been very surprised of seing my acute HEP b to become cronic and never seen a case like mine (not even liver enzimes above normal levels , not even high viral load !!)  what made me feel so afraid at the begining but..........what tha hell I am a worrior I will defeat this virus one way or another !! .  I wish u the best optimistic approache !

[stef2011]

no hbvdna is totally useless to see if you are clearing hbv even if undetectable it means nothing, it is never undetectable in the liver until hbsag und and hbsab high

antibodies like astragalus or beta glucan?
yes, useless, on chronic hbv immune system is controlled and suppressed by hbv, only pegintf has effect

[Magda123]

Sure you will win the fight! did you take some supplements to help with antibodies like astragalus or beta glucan?

[Magda123]

Does hbv dna say something? and elevated wbc?

[Magda123]

Haven't tested hbsag yet but hbvdna is 580iu/ml.

[stef2011]

as i posted before it is extremely easy to know what is going on by hbsag quantity tests because:

chronic carriers have hbsag quant in the thousands range, mostly 5000iu/ml to 250.000iu/ml

immune control has less than 1000iu/ml (genotype a-d), hbvdna less than 2000iu/ml

if you are still acute and clearing your hbsag must be less than 1000iu/ml if higher you have zero immune control and it is going towards chronicity, you can also do 2 tests onemonth aprat and if results are stable or rising again it is chronic, if they are slowly on the decline in the 1000iu/ml raneg acute and clearing

[Magda123]

Despite negative hbcab igm now, it is still acute? Again it was reactive last end of jan.. I've seen a graph that hbsab will start to rise after 6months from infection. I am right?

[GARBANZO]

Hi Magda.  Don't worry.  I got infected in Sep 2011.  Last test in 2/2013 showed a HBSab + = 3 ui.  I have not eliminated the virus so I am not cured but It's better than nothing !!  I am fighting against it !!  who knows maybe one day i will win fight.  getting infected as un adult is not as bad as being as a child.

I just wanted to tell you that according too my doctor It is up to one year to create HBSab so U have time !!  It is important not to stress and be fine in your mind so your boddy will fight efficiently !

[stef2011]

try to boost immune system as i suggested in previous posts and then follow hbsag quantity to know what s going on

[Magda123]

It could not be long time since i even donated blood 3 years back. My husband as well donated blood last september 2012. btw, hubby got infected but cured with hbsab. so i suspect contracted it last october 2012. After 6mos which is april, hbcigm abs non reactive, hbcabs (total) is reactive.