I need urget help on HBV--Please help me

[nihi120]

I am male and my age is 29yrs. Last week I come across that HBV virus in my blood. I had some stomach infection too. I Consulate with Dr. Mahesh K Goenka in Kolkata, India. Then I went for some test , test result are
LFT-
Serum Total Protein(Biuret)        7.5g/dl                         (6.4-8.3 g/dl)
Serum Albumin (B C Purple)       4.4g/dl                         (3.5-5.1 g/dl)
Serum Globulin                          3.1g/dl                         (1.8-3.6g/dl)
Ratio                                         1.4:1:0                        (1.0-2.0:1.0)
Serum Total Bilirubin(jendrassik Grof)  0.6mg/dl               (upto 1.0mg/dl)
Serum Direct Bilirubin(Diazo Method)  0.1mg/dl               (0- 0.2mg/dl)
Serum SGOT/AST(UV Kinetic)       57U/L                          (10-42U/L)
Serum SGPT/ALT(UV Kinetic)        58U/L                          (10-40U/L)
Serum GGT(SZASZ)                          12U/L                       (07-64U/L)
Serum Alkaline Phosphatase(PNP-AMP) 99U/L                  (53-128UL)


Hepatitis B Surface Antigen            Reactive
Value                                                          1211                 (0.0-1.0)

Anti HBc IgM, HBeAg

HBE ANTIGEN DETECTION
HBe ANTIGEN                                              Postitive(Index 4.79)        (Positive:Index>01)
Method Used      Enzyme Linked Immunofluorescent Assay

ANTI HBC ANTIBODT(IGM)
Anti HBc-IgM                                            Equivocal(6 IU/ml)                              Negative 10 IU/ml
Method Used      Enzyme Linked Immunofluorescent Assay



HBV DNA Viral Load
4.45x10^9 viral copies/ml (Four billion four hundred and fifty)

USG U/A
Ultrasound Report shows liver and kidney is normal.


P Time(Prothrombin Time)
Test         15.6secs
Control    14.4secs
INR( International Normalised Ratio)  1.09

Serum Triiodothyronine(T3)        1.1ng/ml                             For Adult(0.8-2.0)
Serum Throxine(T4)        12.8ug/dl                                       For Adult(5.1-14.1)
Thyriod Stimulating Hormone(TSH)        2.3ulU/mL                For Adult(0.27-4.2)


Dr. given me Tab RAZO 20mg, Tab Domstal 10mg, Tab Silybon 140mg TDS, Cap VSL#3 for 15 days and After 15 days he will check again. I thought these medicine for my stomach problem.
For HVB he told you have hepatitis B  not chronic. you will be  definitely fine. I asked  whether I need some more test like hbsag quantity and fibroscan. He told me not required now. After 15 days you come and meet me.

So please tell whether my Doctor is in right way or I have to consult some other doctor? Aslo tell me whether these medicine have any side effect which may be increase my HBV. Can my HVB cure as doctor told.
Please help me.

[nihi120]

Please Suggest me some vit d3 tablet.

[stef2011]

endless brands, puritans vit d3 5000iu are cheap

[nihi120]

Hi,
Its already 6months gone through all test again. It bad news that i am become chronic. My resent test reports are-

HBeAg- Reactive (Sample/cut-off ratio s/co- 560)( Method- By chemilumiscence)

[stef2011]

you need all panel:
hbsag quantity in iu/ml
hbcab igm, if possible quantitative in s/co
hbvdna in iu/ml
ast/alt

according to hbvdna level treatment by tdf+intf may be the best choice but only after you check all panel and according to hbsag/hbvdna levels

hbsag can be cleared in 12 months too if hbcab igm is still positive or if hbsag is going down

[nihi120]

Hi,
Its already 6months gone, I have gone through all test again. It bad news that i am become chronic. My resent test reports are-

HBeAg- Reactive (Sample/cut-off ratio s/co- 560)( Method- By chemilumiscence)

Anti HVC- Non-reactive( method Elisa)

Anti HBe - Non-reactive(Sample/cut-off ratio s/co- 27)(Method- By chemilumiscence)

HBsAg Quantification-  37903 IU/ml(Method- By chemilumiscence)

Fibro Scan- Success rate 100%
                      Cap(db/m)                                      E(kPa)
                      Median 199                                      3.5
                      IQR* 24                                           0.5
                      IQR*/med 12%                                 14%
HBV DNA-
            Method- Real Time PCR
           Instrument- Real Time PCR
           Sample- Plasma
           Result -   >1.10x10^8 IU/ml
LFT-    AST/SGOT            42          (5-40)
           ALT/SGPT            65          (5-40)
           S.Total Protein(Biuret)       8.1  (6-8)
           A/G Ratio                     1.38      (1.5-2.5)
USG U/A
Ultrasound Report shows liver and kidney is normal.


By see all reports Dr. Said that Virus is still Highly Replicated so you have to start treatment even your Fiboscan and ultrasound looks no damage in liver, medicine given  :-

Interferon(Pegasys 180mg) + Yenofovci  ( once in week)
Viread 300mg 1 dalily


I did some more test but result yet to come
Liver Biopsy
Creatinine
HBV Genotyping

Hi expert see my report and tell me whether my treatment going in right direction or not..any suggestion may be help me so please help me.
      

[stef2011]

very good doctor, its intf+tdf, you have the higgest chances to clear on this combo
hbcab igm?