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Avatar universal

Please See these latest reports

Date- 15-may-2010

SGOT (AST)                                27.00 U/L     (< 37.00)
SGPT (ALT)                                 28.00 U/L     (< 41.00)

HBVDNA                                    741 UI/ML
HbsAg                                        Positive(250 UI/ML)
HbeAg                                        Negative
HbeAb                                        Positive

Date- 26-may-2010

LFT

SGOT (AST)                                17.00 U/L     (< 37.00)
SGPT (ALT)                                 13.00 U/L     (< 41.00)
GGTP                                         22.00 U/L     (8.00 - 61.00)
Alkaline Phosphatase (ALP)         62.00 U/L                  (40.00 - 129.00)
Bilirubin, Total 0.82 mg/dL (< 1.00)
Bilirubin, Direct 0.36 mg/dL (< 0.30)
Bilirubin, Indirect 0.46 mg/dL (< 0.70)
Protein, Total 7.30 g/dL (6.40 - 8.30)
Albumin 4.60 g/dL (3.50 - 5.20)
A : G Ratio 1.70 (0.90 - 2.00)


AFP (ALPHA FETOPROTEIN), TUMOR MARKER       2.34 ng/ml   (< 7.00)

treatment is nedded??
Any other test??
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Avatar universal
what you are think about 'Giant Platelets seen'....
it can be happen because of poor diet?,my diet is being very poor from last some weeks

thanks
Helpful - 0
Avatar universal
i cunsulted to dr. on last satusday, he prescibed me sabivo(telbivudine) 600 mg daily and said to perform biopsy or fibro scan..

can i take sabivo in this condition( see above my result)???
and what is the risk of sabivo(telbivudine)?
Helpful - 0
Avatar universal

crazy doctors, i don t understand where they go unless sebvivo makes presents to them......

you have low hbvdna so you should reach hbvdna und fast but have you seen giudelines?sebvivo is not recommended
have you seen the rates of resistance of sebvivo and hbsag seroconversions?mutation higest together with lamivudine and seroconversions zero.what is the cure of sebvivo on you...zero

since the possibility to clear hbsag on nucs are almost zero i wouldn't risk virus mutations and would choose tenofovir (viread) which has no resistance or interferon as guidelines allow

combination with ntz with any of the choices is strongly suggested

also tell the dctor can i sue you if i have a virus mutation since hbv international guidelines do not allow use of sebvivo as first line therapy?is 1 million usd ok?

you probability of an improvment from where you are now is almost zero, your probability of resistance is high
Helpful - 0
Avatar universal

also ask him if he is going to perform genome analisys for hbv mutations before starting antiviral since latest research has found many patients with nucs primary or secondary resistance naturally present before starting therapy

i do strongly suggest to see other doctors before doing such a stupid choice
Helpful - 0
Avatar universal
many thanks Stefano

do you think that i need treatment?

one more thing doctor suggest me for liver biopsy but he say it is risky,  i am newly married. there is any alternative of liver biopsy such as fibroscan, CT scan or MRI....

i know you are taking ntz from last couple of months.Can you tell me your result please....

Helpful - 0
Avatar universal

absolutely not by antivirals, your immune system is already controlling hbvdna and alt itself and that's the only thing an antiviral can do.you need treatment to make hbsag lower or negative and only nitazoxanide can do that

also interferon might be a choice but since sides can be very heavy no doctor uses it with normal alt low hbvdna but you might try it, my sister's doctor did 15 year ago

i suggest ntz 4 weeks and if you see result you might add interferon or keep ntz mono
Helpful - 0
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