Rapid increase in ALT and AST (I am in panic, please help)

[SafiSifa]

Dear Friends,

I am on Entecavir treatment for 5 months.

5 months ago
ALT: 86
HBV DNA: 557 000 000

2 months ago
ALT: 90
HBV DNA: 55 000

This Week
ALT 347
HBV DNA: not resulted yet.

As you see my ALT increased rapidly in the last 2 months. My doctor says It may be because of (1) mutation or (2) sport+eating protein. They want me to wait HBV DNA result.

Dear Stef and other friends. Please share your comments. I am in panic.

Regards.

[SafiSifa]

Dear Stef,

I thank you a lot for your valuable contribution.

I have a four questions for you and others;

1. "the good thing is that hbsag goes very low usually, it would be good to have it tested too" what do you exactly mean? I do not understand.

2. My ALT increased from 90 to 347. my immune system is activated to fight with HBEAG and produce ANTI-HBE. There are very effective natural supplements to lower down the ALT, such as; parsley cure and lavender cure. I tried lavender cure before my treatment (5 months ago). On the other hand, there are also very effective immune booster natural supplements (may increase ALT), such as; kephir. Should I try to lower my ALT with something lavender cure, or should I try to help my immune system (which may cause ALT increase) with something kephir?? Please answer this by considering my biopsy is F3 and fibroscan is 6.6

3. My HBV-DNA is still positive (26000) and my ANTI-HBE is negative. Is it a bad sign? Does it mean any drug resistance?

4. Is it possible that the seroconverting period makes me cirrhosis?
  

[stef2011]

by the way it made no liver damage and liver was very little enlarged

[stef2011]

you are seroconverting hbeag and soon will have hbeab positive

the flare is low so it will probably take long for hbeab to become positive, the good thing is that hbsag goes very low usually, it would be good to have it tested too

just for you to compare, my natural hbeag seroconversion happened at about 18yo with 6 months of alt over 1500....to bad at that time there was only experimental use of peg and no hbsag quantitative even in research hospitals, add ing pegintf at that time (if my hbsag was low) would have cleared hbv for sure

[SafiSifa]

Hello Stef, andrey19, grmr, mustthinpositive, and other friends.

You know my last story (if you do not know, see above..)

I got the test results today.

HBV DNA came down from 55000 (it was 557 million 5 months ago) to 26000.

And my HBEAG is seroconverted. My ANTI-HBE is negative (1.57).

ALT is increased 90 to 347 in the last 2 months.

So, could you share your comments for the latest situation?
Shoul I be happy or be sad with the results?

Thnx.

[SafiSifa]

So, this is a good news for me, right?

[SafiSifa]

Thank you Andrey19.

What I understand from the article above is that my viral load and e antigen are decreasing strongly and that is why my ALT flared, right?

Sorry for my poor English :(