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Regarding HBV DNA quantitative test results
hi,
i am a male and was found positive for Hepatitis B about two years back. doctors say i am just a carrier. My recent LFT gave SGPT count as 56 which is out of the range of 13-40. so i got my HBV DNA quantitative test done. the result came out to be as "under detectable limit". what does this conclude?
i don't consume alcohol and am a healthy person as a whole.
1) Is the hepatitis B virus not replicating in my body?
2) Also i want to know the chances that my wife who has taken the vaccination for Hepatitis B gets this virus from me?
i am a male and was found positive for Hepatitis B about two years back. doctors say i am just a carrier. My recent LFT gave SGPT count as 56 which is out of the range of 13-40. so i got my HBV DNA quantitative test done. the result came out to be as "under detectable limit". what does this conclude?
i don't consume alcohol and am a healthy person as a whole.
1) Is the hepatitis B virus not replicating in my body?
2) Also i want to know the chances that my wife who has taken the vaccination for Hepatitis B gets this virus from me?
thanks enolia,
can you tell what are the most common reasons for elevated ALT other than HBV? would consistent elevated ALT cause liver damage even if it’s not attributed to HBV ? if yes, is liver damage reversible?
thank you.
sami
can you tell what are the most common reasons for elevated ALT other than HBV? would consistent elevated ALT cause liver damage even if it’s not attributed to HBV ? if yes, is liver damage reversible?
thank you.
sami
is it the quantitative HBsAg ?
yes but since most doctors and labs are ignorant on this and don t know the test i will write the machine, the kit and the process to be used by the lab.
abbott architet hbsag quantification in iu/ml, range 0.05-250iu/ml and if higher than 250iu/ml diluition 1:1000 is needed
so if you find hbsag<500iu/ml and you still have hbvdna at 65iu/ml you are inactive carrier in clearance phase
should I do then with the elevated ALT and SPGT ? what is the best line of action now ?
if alt are little elevated between 30 and 50 you might keep monitoring every 6 months or try alinia treatment if hbeag is negative/hbeab positive and hbsag low
alinia will make hbvdna und, alt normal and will lower hbsag and possibly make it negative by 1-2years
less than f2 should I just ignore the elevated ALT and SPGT and live normal and re-test after 6 months.
yes because the liver damage is very little but instead of just monitor i'd try alinia treatment
a good way to have normal alt and prevent fibrosis or reduce it:
153gr of bluberries everyday, 3 cup of coffee, cocao in powder without sugar from time to time you can make like liquid choccolate with no calories sweetner, no fats and all fresh food or frozen
alt can be elevated by unhealthy diet, alcool (elevated like cronic hbv), a lot of excercise/gym/sports
yes but since most doctors and labs are ignorant on this and don t know the test i will write the machine, the kit and the process to be used by the lab.
abbott architet hbsag quantification in iu/ml, range 0.05-250iu/ml and if higher than 250iu/ml diluition 1:1000 is needed
so if you find hbsag<500iu/ml and you still have hbvdna at 65iu/ml you are inactive carrier in clearance phase
should I do then with the elevated ALT and SPGT ? what is the best line of action now ?
if alt are little elevated between 30 and 50 you might keep monitoring every 6 months or try alinia treatment if hbeag is negative/hbeab positive and hbsag low
alinia will make hbvdna und, alt normal and will lower hbsag and possibly make it negative by 1-2years
less than f2 should I just ignore the elevated ALT and SPGT and live normal and re-test after 6 months.
yes because the liver damage is very little but instead of just monitor i'd try alinia treatment
a good way to have normal alt and prevent fibrosis or reduce it:
153gr of bluberries everyday, 3 cup of coffee, cocao in powder without sugar from time to time you can make like liquid choccolate with no calories sweetner, no fats and all fresh food or frozen
alt can be elevated by unhealthy diet, alcool (elevated like cronic hbv), a lot of excercise/gym/sports
all damage can regress but the more fibrosis the longer to regress.only uncompensated cirrhosis cannot regress but in this case you are close to death and should never arrive at that point, cirrohis is f4 metavir scale or fibroscan higher than 12-13kpa
my DNA count is 20IU/ML is it high?what is normal range of DNA count?please help i m hbsag positive ANTI Hbe positive HBEAG negitive,am i healthy carrier?
my DNA count is 20IU/ML is it high?my hbeag is negitive ANTI Hbe positive.am i healthy carrier last year i come to know i m hepatitis b positive pls help.i need any medication or not
my DNA count is 20IU/ML is it high?
no very very low
my hbeag is negitive ANTI Hbe positive
alinia (nitazoxanide) might help get hbsag lower or negative by 1-2 years therapy, the other option is monitor since all other drugs are not active on hbsag and can make only damage in your hbv phase
am i healthy carrier?
if hbsag is lower than 500iu/ml, hbvdna stayes lower than 2000iu/ml, alt normal you are a healthy carrier.if hbsag>500iu/ml your are in inactive phase and as long as alt are normal and hbvdna7kpa are to consider, values>10kpa severe liver damage, >12.5kpa cirrhosis)
i need any medication or not
there is no drug active on hbv, they can only lower hbvdna when liver damage is severe and prevent more damage but as long as hbvdna<2000iu/ml you have nothing to worry and with hbvdna at 20iu/ml you are perfectly ok.do not strat nuc or interferon for now since these have sides and can only make damage to you now
the only option might be off label therapy with alinia, it is active against hbv and in hbe negative might get hbsag negative by 1-2years.when hbsag gets negative hbsab antibody gets positive and you have eradicated hbv (eradicated i mean immune system have total control), hbsab antibody blocks viral entry so hbv cannot enter liver cells and we can condier it as hbv cured
no very very low
my hbeag is negitive ANTI Hbe positive
alinia (nitazoxanide) might help get hbsag lower or negative by 1-2 years therapy, the other option is monitor since all other drugs are not active on hbsag and can make only damage in your hbv phase
am i healthy carrier?
if hbsag is lower than 500iu/ml, hbvdna stayes lower than 2000iu/ml, alt normal you are a healthy carrier.if hbsag>500iu/ml your are in inactive phase and as long as alt are normal and hbvdna7kpa are to consider, values>10kpa severe liver damage, >12.5kpa cirrhosis)
i need any medication or not
there is no drug active on hbv, they can only lower hbvdna when liver damage is severe and prevent more damage but as long as hbvdna<2000iu/ml you have nothing to worry and with hbvdna at 20iu/ml you are perfectly ok.do not strat nuc or interferon for now since these have sides and can only make damage to you now
the only option might be off label therapy with alinia, it is active against hbv and in hbe negative might get hbsag negative by 1-2years.when hbsag gets negative hbsab antibody gets positive and you have eradicated hbv (eradicated i mean immune system have total control), hbsab antibody blocks viral entry so hbv cannot enter liver cells and we can condier it as hbv cured
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