Should I stop Hepsera?

[viet29]

I been taken Hepsera 10mg daily for 6 years now and the virus is undetected. Today my doctor told me to stop to see my body could suppress the virus it self. Should I stop or keep taken it? will my condition get worse? what if it didnt work and I take hepsera or viread and develop resistant? Help or personal experience would be great. Thank you

[stef2011]

ship samples by fedex to the indian labs willing to make the tests or if you happen to travel to europe, asia or some african countries you can check hbsag in that occasion

we posted indian labs because very good and cheap

[viet29]

To bad for me, I live in the US and ask you said qhbsag are not available. So what are my option testing for more accurate of the virus?

[stef2011]

that hbvdna is obsolete, too poor sensibility, you need a test with hbvdna<10iu/ml but if you combo with peginterferon this has no importance

if you are in US, US is 10years obsolete on tests and for market reasons dont allow use of hbsag quantification which are available every where in the wrold (UK,US, australia excluded)

no switch tdf+intf but you need a lab for hbsag quant otherwise you can see if you are clearing hbv

what are the rate of clear hbv in asian tdf+interferon? how long is the treatment?
see other posts in the forum.one study with peg add on on stable long term nucs had:
40% hbsag clearance at 48weeks
10% non response
50% with hbsag at very low levels like 30-300iu/ml (which is nothing) after 72 weeks on the combo.the combo, if responder, is meant to be kept until hbsag und

[viet29]

thank stef2001 for the reply.
I dont understand the difference between hbsag quant and hbv dna?
my lab
hepatitis B viral DNa
hep b viral dna iu/ml           <100 in range
hep b viral dna copies/ml    <160 in range
my other lab
Hbv, Qualitative PCR hbv Dna not detected
both lab work perform by two difference lab.

So what your recommend stop and see couple month to see the the virus progress or just switch to TDF+interferon?
what are the rate of clear hbv in asian tdf+interferon? how long is the treatment?

[stef2011]

hbvdna checking is useless, it must be und but it means nothing to curing hbv

you should check both hbsag quant in iu/ml and hbvdna and then switch to tdf+interferon to clear hbv

[viet29]

should I stop 3 month and check hbv dna and if it not good then switch to viread (tenofovir) or viread plus peginterferon?