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Treatment ? Clinical Trail?
Hi, i have very little knowledge of Hep B and apologize ahead of the time for stupid questions.
Background: found out i'm hep b carrier at age 16, when my brother was tested positive, the whole family went for testing, and i was the unlucky one, my mom for some reason was tested negative, but my dr. believe it was from my mom, that my mom's result was false negative. She never re-test. I'm female and 35 years old now. My previous dr. (2003-2012) always says that since my liver function is normal, no medication is recommended even though my viral count was high. then i moved an have a new dr since 2012, he however believes that i should take tenofovir because my viral count is high, but he said it's my choice and i could take time to think about it. so when i finally decided to take this medicine, he said there's now a new trial on going, and it might cure hep b, and i'm a perfect candidate for it. So it's the Gilead's trial of " Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Subjects With Chronic Hepatitis B and Who Are Currently Not on Treatment"
I'm scare of the side effects, and read that there was death on a previous hep C trail.
I have no medical knowledge and wanted to know if there's any danger in clinical trial. what are the pros and cons? If i don't do it, and this trial is successful, how soon will the medication be available?
my test result as of july 2014,
HEPATITIS BS AG - Reactive
HEPATITIS Bs Ab QUAL - Non-reactive
ALT-23
AST-22
ALPHA FETOPROTEIN - 2.9
FERRITIN - 10
HEPATITIS BE AB - Negative
HBV DNA QUANT. PCR - 122,189,878 iu/ml
HEPATITIS BE AG - Positive
i read many posts by the community, and it seems like i need to get HBsAg quantitative number, which i didn't see from my result, just email my dr to get that.
thank you all.
Background: found out i'm hep b carrier at age 16, when my brother was tested positive, the whole family went for testing, and i was the unlucky one, my mom for some reason was tested negative, but my dr. believe it was from my mom, that my mom's result was false negative. She never re-test. I'm female and 35 years old now. My previous dr. (2003-2012) always says that since my liver function is normal, no medication is recommended even though my viral count was high. then i moved an have a new dr since 2012, he however believes that i should take tenofovir because my viral count is high, but he said it's my choice and i could take time to think about it. so when i finally decided to take this medicine, he said there's now a new trial on going, and it might cure hep b, and i'm a perfect candidate for it. So it's the Gilead's trial of " Safety and Efficacy of GS-4774 in Combination With Tenofovir Disoproxil Fumarate (TDF) for the Treatment of Subjects With Chronic Hepatitis B and Who Are Currently Not on Treatment"
I'm scare of the side effects, and read that there was death on a previous hep C trail.
I have no medical knowledge and wanted to know if there's any danger in clinical trial. what are the pros and cons? If i don't do it, and this trial is successful, how soon will the medication be available?
my test result as of july 2014,
HEPATITIS BS AG - Reactive
HEPATITIS Bs Ab QUAL - Non-reactive
ALT-23
AST-22
ALPHA FETOPROTEIN - 2.9
FERRITIN - 10
HEPATITIS BE AB - Negative
HBV DNA QUANT. PCR - 122,189,878 iu/ml
HEPATITIS BE AG - Positive
i read many posts by the community, and it seems like i need to get HBsAg quantitative number, which i didn't see from my result, just email my dr to get that.
thank you all.
Best Answer
Hi Rach! I buy through e-bay or amazon Solgar Vit D 10.000. I can'drink coffee without milk for sure. I eat everything, except sugar. Since I know for hep b , I put honey instead of sugar, sleep a lot. Since two years I am reading everyday about tenofovir. It is the only potent and effective drug with no resistance, and everyone taking it is feeling fine. No side effects, mostly could occur to people with coinfection with hiv. Just listen your doctor, he is a warrior, he won his battle trying antiviral with interferon, he also put himself on clinical trial. He is a scientist.
And on that note, any diet/food is particular helpful? thinking about Vit D, i'm not a milk drinker, never was, should i really start drinking milk for the sake of my liver? any other tips is appreciated.
I understand there's a lot of great threads here, feel free to link it here for me to read if it's already discussed elsewhere.
I understand there's a lot of great threads here, feel free to link it here for me to read if it's already discussed elsewhere.
Sent you a mdm Mer971.
By the way, i'm starting to religiously taking Vit D3, what brand and dosage is good? would you guys suggest any?
Thanks.
By the way, i'm starting to religiously taking Vit D3, what brand and dosage is good? would you guys suggest any?
Thanks.
Well, they are not providing the vaccines after the trial. I read Gilead is obnoxious with putting a high price tag on their medicines. Ugh...
Hi rach. I live in NY as well. Could you tell me who is your dr?, or send me sms inbox. Meanwhile,they don't do Hbsag test here, if you have chance to go outside usa do it. If you choose to go on trial, I will be curious if they test people for hbsag before going in, or it is a game of healthinsurance, or what's the problem? such a cheap test
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