sir,
your information of HBA +ve is very very useful, to the
mankind . thanks..
karunanidhi
DNA undtectable does not mean that you have no virus in you. As long as you are S antigen positive that means the virus is replicating (S antigen is released when the virus reproduces).
It means you have little virus circulating in your blood but it still is replicating in your liver. There is a correlation with DNA in your blood and damage to your liver but not in the low numbers you have. Some people have counts in the billions.
Its a cycle. Sometimes the virus becomes dtetecble and then it goes undetectable and so on.
Thanks jboyk
Does DNA determine how much liver damage is going on or does alt/ast?
Also, how can one go from undetectable to all of a sudden 15,000? I'm just curious what causes such a fluctuation.
Also, what does it mean when your dna fluctuates and alt stays in normal range? Shouldn't both be high if one fluctuates?
Thanks again
http://www.hivandhepatitis.com/hep_b/tests/6.html
This is how I would classify you
"(i) Chronic HBV carriers with no detectable HBV replication. Small amounts of HBV DNA may however be detected in these patients with recently developed highly sensitive PCR-based assays. Ongoing studies are aimed at determining the threshold above which HBV replication should be considered clinically relevant."
A few years back, the best tests were only able to detect above 150,000.
Treatment with antivirals is not recommended for your very low viral count. It will ebb and flow (detectable to nondetectable) but very low.
You should get treatment if your AST/ALT rises and your DNA rises over 100,000.
There is nothing I see out of the ordinary here. Studies have shown that over a period of time you go from undetectable to small detectable in DNA count for an inactive carrier.
Don't quote me on this number but I believer precore mutants would generally have well over 100,000 DNA copies (and usually millions). Precore mutants would also have raised AST/ALT which you don't have.
Your AFP is notthing to worry about at those levels and it just seems you are a normal inactive carrier.
Also the DNA test usually does take a couple of weeks to get back so nothing unusual there.