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Avatar universal

What now?

Hi Everyone,
First off I would like to thank everybody here for contributing to the forum. You guys have provided an enormous amount of information and support for everybody. Ever since I found out I had chronic hepatitis B, I was in shock. My life totally changed for the worst. I use to have a wonderful social life and everything, but now it's the total opposite. I'm hoping in the future my social life can slowly return to some degree of resemblance. I know I have to take care of my liver from now on and try to stay away from alcohol. Ever since the doctor told me to avoid alcohol, I touched it very little - a little sprinkle of whisky with a glass of soda, or mixing 1/3 glass of beer with water.
I just got the results from my last blood test. The doctor congratulated me and told me that HBV DNA was undetectable and that my liver was no longer inflamed, AST was 28, and ALT was 38.
Just back on 30 June 2010 my blood test showed the following:
Hbsag pos
Anti hbs neg
Anti hbc igm neg
Hbeag pos
HBV DNA > 110,000,000 IU/ml
Liver biopsy: marked piecemeal necrosis, mild intralobular degeneration, moderate portal inflammation, fiberous portal expansion. Knodell score: 9.
Diffuse alteration of the periportal plate in all portal tracts, absent of bridging and confluent necrosis, at least one necroinflammitory focus per lobule, mononuclear aggregates in all portal tracts and stellate enlargement of portal tracts without septae formation. Metavir score: 7

Here are test results for 2005 and the past few months:
29 Sept 2005
AST 20
ALT 23

3 Aug 2010
AST 115
ALT 308
Does this mean that I contracted Hep B sometime between 2005 and 2010?

17 Aug
AST 112
ALT 230

14 Sept
AST 202
ALT 355
I think my enzyme levels increased during this period because I smoked pot for 3 nights straight thinking that it wouldn't affect my liver. Was I wrong!

26 Oct
AST 28
ALT 38
HBV DNV undectable

How meaningful are the above results? Or is it too early to tell?
I began my first injection of Pegasys back on 3 August and have already taken 13 injections. My question is what now? The doctor tells me that I have to take Pegasys until the very last injection (injection 48). Is this true or does he just want my money?
Is there any chance that I may have immunity now? Or is it too early to tell and I just need to continue taking the Pegasys injections?
What are the chances that I will seroconvert and test HbSag (Negative) and HbEag (Negative) in the future? When should I go get tested again?
Does this mean that my liver can begin repairing itself now? Will my liver be able to return to its original state before I contracted the virus?
In my current state, do I still need to stay away from alcohol? Can I drink once in a while? Should I wait until my very last injection before taking a drink?

Thanks everyone.
32 Responses
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Avatar universal
i had chronic hep b and i was 48 weeks on theraphy pegasys + lamividin. U will see your antibodies, wait.
One day i had some reaction like vaccine reaction ( vaccine for flu), everything hurt me.
In two days i was going to test for antibodies and i had >1000. I told to my doctor for that reaction and he told me that he is not sure that si reaction for hbs antibodies but that i am lucky man.
Helpful - 0
Avatar universal
I'm 34 from Laos.
It's really amazing how you now have antibodies. How did you first find out that you had chronic hep b?
Helpful - 0
Avatar universal
i am 29, from Serbia.
U?
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Avatar universal
@hepdeck
Doctors and both hospitals never tested me for genotype. I don't know why. Maybe almost all CHB carries in SE Asia have a predominant genotype. Btw, how old are you and where are you from?
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Avatar universal
do u know what is your genotip of hbv?
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Avatar universal
yes its possible, i have immunity, anti-hbs +, titar>1000, titar must be high then 10.
but i was anti-hbs positive 4 weeks after teraphy, my doctor told me that i supose to be positiv after 24weeks but i was after 4. Some people can be positive after 96weeks, some for the time theraphy.
i didnt take nothing except theraphy.

did u have so big alt and ast first 12 weeks(my ast/alt 2000/3000), after 12 weeks 20/30?
my last analysed ast/alt 8/12, when i cured, and last mounts i eat evrerything, fast food, pork, coca-cola, alcohol, red bull. but its normal(ast/alt 8/12) when i am cured.
Helpful - 0
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