Aa
alinia
did anybody try alinia with hbv?
it is strange nobody tried it yet since it is not expensive and available at pharmacy
it is strange nobody tried it yet since it is not expensive and available at pharmacy
virologic response is low hbvdna or undetactable, a response of only 27% on hbvdna is very very little if there was no hbsag seroconversion.
so it really doesn t worth to try it monotherapy but since it has no sides a combo with other immune modulating drugs like interferon or alinia can be interesting to see
Himalaya sees huge potential for Liv 52 HB, hopes to make it Rs.10 cr brand
Nandita Vijay, Bangalore
Friday, May 27, 2011, 08:00 Hrs [IST]
The drug development process at Himalaya follows allopathic protocols to determine safety and efficacy as per the World Health Organization (WHO) guidelines. Approximately 1,000 patients took part in the clinical studies for Liv.52 HB across the country for six years which began in 2004 and continued till 2010. There were five double-bind placebo-controlled studies. Fifty percent of the patients were administered the active drug and the other 50 percent were given the placebo. Sustained virological response was seen in more than 27 per cent of the patients. The clinical trials were conducted in hospitals across the country, including Bangalore where it was undertaken in Victoria Hospital, Bangalore, amongst others.
Nandita Vijay, Bangalore
Friday, May 27, 2011, 08:00 Hrs [IST]
The drug development process at Himalaya follows allopathic protocols to determine safety and efficacy as per the World Health Organization (WHO) guidelines. Approximately 1,000 patients took part in the clinical studies for Liv.52 HB across the country for six years which began in 2004 and continued till 2010. There were five double-bind placebo-controlled studies. Fifty percent of the patients were administered the active drug and the other 50 percent were given the placebo. Sustained virological response was seen in more than 27 per cent of the patients. The clinical trials were conducted in hospitals across the country, including Bangalore where it was undertaken in Victoria Hospital, Bangalore, amongst others.
yes HD-03/ES is Liv52 HB. there are some 6 research papers in the site that i mentioned (http://www.himalayahealthcare.com/researchpaper/liv52-hb.htm) and please go through them and let us know. My siddha doctor ( he is working at Central government siddha research institute in chennai, India) said we can trust Himalaya's products compared to others. But only results can tell us whether this drug is working or not.
check also the study i have found about cellular cholesterol and hbv assembly, the interference happens well before hbsag and cccdna so it is sure to help although we dont know how much
and we also dont know how much liposomal gsh can lower cellular cholesterol. we do need the UK researchers who studied lipo gsh on rats and saw arterosclerosis regression by 3 months use, they should have an idea of what ghs does inside the cells
there cannot be an answer to this but alinia is reported to have little influence from or on other drugs
it is better to wait in ur situation maybe because you are close to seroconvertion and act on these combos only if hbsag tends to increase to 1000iu/ml
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