hepatitis b SGPT SGOT are rising

[sleepyeinstein]

date: 07/07/2012:my SGOT=109IU/L SGPT=292 IU/L
date :29-may-2013:my SGOT =233 IU /L ,SGPT=504 IU/L
can any one explain SGPT ,SGOT Levels?
why these values are  rising ?
what is the  dager level of SGPT  & SGOT ?

[newtr]

most probably you are in clearance phase so sgpt is increasing but not sure. can say anything after few months. do the above tests including sgpt and cbc, monthly or bimonthly and dna quantative after each 4 month to monitor.

[sleepyeinstein]

i've took  many test as suggested by doctor here are the details
date: 2013-05-08

Molecular Biology

Hepatitis b viral load
method :real time PCR
resukt(iu/ml) >10000 0000(8 zeros)
result(copies /ml)>70000 0000(8 zeros)

immunology /serology

hepetitis b envelope antibody(antiBHe) --5.46 --units[S/co]-method:ELISA
hepetitis b envelope antigen(HBeAg)--7.01-units[s/co] -method:ELSIA
hepetitis b surface antigen(HBsAG)-10.28-units[s/co]--method:Elisa


Clinical biochemistry

alpha Feto Protein (AFP)-serum --results 5.2--units IU/ml
method :chemiluminescenece

[Rome70]

With such viral load no wonder alt is high, do you take any medicine?

You should take antivirals Tenofovir is the best so far.

Also you need to do fibroscan and ultrasound. And you need a doctor who knows about hbv, not just GP or GI.

[newtr]

hbsag quantative is not in iu/ml and useless without units.
high viral load is common in young age due to immune tolerance so dont worry and dont hurry...remember strictly...dont hurry.. check vit d level and report us. steff is studying vit d effect on hvb.so please report here.

this may be not right time for antiviral treatment as you are entering in/entered in immune clearnace phase plus your age is less, so if possible wait and see for a year. if you strictly want to start treatment go for interferon, in india local brands at 5000 rupee/shot are available. it may be good as alt is high. try it for 3 months and see. while on interferon go for hbsag quantative test with dilution  in iu/ml units before starting interferon and then after each month.. may be available in india under some dr. lal pathlabs..talk their customer care.

[sleepyeinstein]

the doctors also took the ultrasonography abdomen
date:4-02-2012

Liver :Normal in size and echo pattern.No evidence of any focal lesions,No evidence of IHBD

gall bladder:Distended.No evidence of any calculi.No  evidence of wall thickening . NO evidence of peri cholecystic fluid collections

CBD: Not dilated(measuring 5mm .arppr.)
portal vein : Normal in calibre( measuring 8mm .arppr)
pancreas : Normal in size echo pattern.pancreatic duct not dilated.No evidence of any peri pancreatic edema/collections

spleen : noral in size and echo pattern(measuring 11mm .arppr)

kidneys: normal in size .cortical echogenecity normal.Cortico medullary differentiation is maintained.No evidence of any calculi.No evidence of hydronephrosis.No evidence of  cysts.
             RK:9.6x4.7 cm .LK :9.3x 4.5 cm.

Urinary bladder :distended.No evidence of any calculi.No evidence of wall thickening.
prostate : Normal in size
*IVC & Aorta-normal
*No evidence of  free fluid in the abdomen/pleural effusion.
*No evidence of lymphadenopathy.

IMPRESSION : Essentially normal Study .
      

[sleepyeinstein]

my doctor suggests me to take a pegasys (exxura) of Hoffmann-La Roche