without treatment you better it does not start, it is immune system to damage the liver without making any difference to hbv.
you have to start tenofovir or entecavir for 5-10years to repair your immune system and then add peg, all the rest is just wasted time since 10years is not short
hcc is due to high viral load or hbsag or both ? can appear at any age/phase/fibroscan score etc or its just bad luck ?
it is not known exactly but if you clear hbsag by the age of 50yo you lower the risk like those who were never infected, if you clear later it makes no difference
i think hcc is due to our immune system not clearing hbv and making inflammation and cellular damage.i read a study long time ago that said cells degenerate to hide from immune system and not being killed...maybe also this is part of hcc degeneration but it is probably a mix of inflammation, hbv integration in our dna.......how you prevent it for sure:
making hbsag less than 1000iu/ml on hbeag neg and of course no hbvdna and fibroscan less than 5kpa
on hbeag pos/immune tolerant there is very little immune response so the HCC risk is very low whatever
and do you think with low fibroscan like 4.2 is it necessary to star nucs immediatly?
melcul few days before you waited for my check here it is but sure next time i will take treatment ,what about you?