http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532295/
Positive correlation between circulating cathelicidin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults
but i have found other studies on different diseases from tbc to sepsis, psoriasis and so on....phatogens make this correlation very weak, they probably influence this balance by nagalase and other ways to block vdr receptor so that no LL37 cathelicidin is produced
this is very interesting
http://rrml.ro/articole/2013/2013_1_11.pdf
The serum level of the immunomodulatory peptide
cathelicidin LL37 and T helper cell type 1 inflammatory
response in viral hepatitis B, C, and D
inactive hbv has been found with:
LL37 serum level (ng/ml)±SD 174.66
IFN-γ serum level (pg/ml) 70.23
CD4 cell count/mm3±SD818.80 ± 358.66
CD8 cell count/mm3±SD551 ± 340.85
CD4/CD8 ratio ±SD1.37 ± 0.62
active hbv has been found with:
LL37 serum level (ng/ml)±SD 76.75
IFN-γ serum level (pg/ml) 24.57
CD4 cell count/mm3±SD866.88 ± 352.03
CD8 cell count/mm3±SD539.85 ± 176.31
CD4/CD8 ratio ±SD1.64 ± 0.41
so just my guess the higher the vit d, the higher gcmaf (which equals lower nagalase), the higher LL37 serum level from immune cells and LL37 has an antiviral effect
they found that:
immune cells have vdr receptor to be activated, this receptor needs vitd+oleic acid+gcmaf in order to have immune cells activated so they made a type of vit d which has the oleic acid included....if any of these is missing there is no attachment to vdr receptor
https://www.youtube.com/watch?v=Bu0AuPo50_k
minute 07:58
what should be the method. oleic acid add on with normal vit d or some other method or compound.
hbsag quantity and hbvdna, ast-alt should be measured baseline and then every 4 weeks together with vitd25oh to see if this form can have more activity on hbv