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vit d3 82ng/ml and lowering alt, not on therapy


my sister just got tests results and the patern of hbvdna, alt looks inversely correlated with vitd 25oh>80ng/ml, this can be confirmed by time, she now has for the first time alt 40, hbvdna stable at around 200.000iu/ml, no liver damage 4.5kpa, hbsag around 18.000iu/ml

probably vitamin d is able to protect liver despite hbvdna detactable keeping alt 40, she will be checking fibroscan and hbsag next month

she has normal calcium as usual and creatinine and check every 3 months with vit d.she has daily vit d3 5000-8000iu
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Avatar universal

forgot cholesterol, she also keeps:
tot chol around 190mg/dl
ldl 100mg/dl
hdl 76mg/dl

by taking red yeast rice from time to time but not continuatively
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Avatar universal
well done stef!

how long has she been intaking vit D3? Are those softgels 5000iu we spoke about?
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Avatar universal
yes, about 1years vit d3 to raise so much

she tried alinia mono in 2010 but didn t work

she s hbeag neg
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Avatar universal
I am curious.  How long has she had elevated alt and hbvdna?  Why isn't she on antiviral therapy?  
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Avatar universal
always

she is not on antiviral therapy because liver has no damage at all so antivirals are useless.
initaly we have fibroscans everywhere so therapy is started only if here is liver damage, hbvdna is meaningless if there is no liver damage
Helpful - 0
Avatar universal
I'm glad to hear that you sister is doing well and that the vit d look like protect the liver.

what was she's base line for vit d (and alt . hvb/dna) ?
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Avatar universal

vit d3 10ng/ml
hbvdna 300.000iu/ml
alt 60-70

if you consider that i was 30-50 with hbvdna und on etv there isn t much difference.

but all this can be done with fibroscan monitoring because alt and hbvdna do not reflect liver damage but in her case they do as confirmed by fibroscan
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Avatar universal
of curse that fibroscan is mandatory for monitoring.

looks like vit d help to low hvbdna and alt and most important keep the same result in fibroscan score.

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Avatar universal

we will keep monitoring if this is the effect of vit d or just coincidence
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Avatar universal
stef are those softgels I'm currently intaking 10000 daily?
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Avatar universal
maybe a goggle excel table with all of this results, base line, previous results ... will be a good tool to see it
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Avatar universal

me and my sister are keeping it, i dont know if she agrees to put all that online but i can post single results
in any case she is feeling defenitely better than when vit d deficent with no colds, flu and so on
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Avatar universal
suggestion was for you and not for public :) (I wasn't aware that you already use it)


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Avatar universal
Happy to hear the good news about your sister.
I have just tested vit D3 level and hbvdna and HbsAg quantative this morning.
Vit D3 and hbvdna results will be ready on Monday and Hbsag quantity will be ready only two weeks later. I'll post it when I have them.
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Avatar universal

i was checking vitamindwiki.com for studies on vitamin d and found that vitamin d increases hdl, i found a link to this trial too and it looks it is possible to get hdl to 80mg/dl or higher.
we do know hdl is antiviral on hbv from a study presented at easl 2010 or 2011, high hdl like 80mg/dl makes also heart diseases/strokes/diabetes to zero and also centenarios are all found to have hdl>80mg/dl

http://www.trackyourplaque.com/blog/2011/11/hdl-80-mgdl.html

then i check my sister's and mine hdl and using vitamin d we both went from:
my baseline hdl before vit d was 43mg/dl, which is lower than normal and linked to fatty liver, metabolic syndrom and so on
my hdl got 65mg/dl  after getting vitamin d higher than 50ng/ml.i am also on omega 3 but never reduced  wheat or limited carbohydrate consumption

my sister was around 50mg/dl and now at hdl 75mg/dl
she is just on vit d, but not reduced carbohydrate consumption and not on omega 3
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Avatar universal
of course this is very beneficial to liver and immune system too, so if anyone wants to try, just make sure to have enough proteins from soia and fish and very very few from meat and cheese

http://www.trackyourplaque.com/blog/2011/11/hdl-80-mgdl.html

HDL 80 mg/dl

Posted on November 14, 2011 by Dr. William Davis
More and more people in my clinic are showing HDL cholesterol values of 80 mg/dl or higher, males included.

Think about it: Nationwide, average HDL for males is 42 mg/dl and for females 52 mg/dl. Even though these average values are generally regarded as favorable, HDL cholesterol values at these levels are nearly always associated with higher levels of triglycerides, postprandial (after-eating) lipoprotein abnormalities, and excessive quantities of small LDL particles.

HDL particles are, of course, protective and are powerfully anti-oxidative. Higher levels of HDL have been associated with reduced potential for cancer, as well as reduced risk for heart disease.

Following the simple regimen that we follow to gain control over coronary plaque has therefore increased levels of HDL to heights that are uncommon in the rest of the population, levels that readily top 80, 90, or 100 mg/dl. That regimen includes:

1) Elimination of all wheat–Yes, consumption of “healthy whole grains” sets you up to have lower HDL levels; elimination of wheat increases HDL.
2) Limited carbohydrate consumption–While eliminating wheat is a powerful nutritional strategy to increase HDL, non-wheat carbohydrates like quinoa, millet, beans, rice, and fruit can still cause high triglycerides that lead to reduced levels of HDL. Limited exposure helps keep HDL at higher levels.
3) Omega-3 fatty acid supplementation–Because omega-3 fatty acids reduce both triglycerides and blunt the postprandial rise in lipoproteins that can cause HDL degradation, HDL rises with omega-3s from fish oil.
4) Vitamin D supplementation–The effect is slow, but it is BIG. HDL just goes up and up and up over about 2 years of supplementation. Before vitamin D, HDL levels of 60 mg/dl were the best I could hope for in most people. Now 80 mg/dl is an everyday occurrence.

Other factors can also be used to increase HDL levels, such as weight loss, red wine and alcohol, exercise, cocoa flavonoids, green tea, and niacin. But following the regimen above sends HDL through the roof in the majority.
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Avatar universal
regarding increasing HDL - have a look on this
http://www.colesterol-stop.ro/en/studiu.html

unfortunately, I haven't have a chance to verify this, but i will verify it and come back to the results (I write a email to the indicated Institute and wait for the reply)
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Avatar universal
that is true but all fish with high omega3 is beneficial, populations on fish diets like alaska or graceland have almost zero problems with heart but i believe vit d has the most part

i will try to check also my father hdl, he was around hdl 40  and glucose 125 with vit d 11ng/ml
with d3 85ng/ml glucose dropped to perfectly normal around 90, first time in years, now i will try to follow his hdl too, i remember he was around 55mg/dl already with d3 85ng/ml but i guess it got higher with time
my father is also on omega 3 and fibroguard
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Avatar universal

i do believe about danube fish but i think there is a lot of pollutants in those waters...if they check fish oil for pollutants and then filter it can be a very good product
i only take the filtered fish oil for omega3 because most fish has poluttants for sure
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Avatar universal
is not fish oil - a fish conserve :) ... don't think that they filter, but I will ask (on the other hand I don't think that is so much polluted at leas not now )
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Avatar universal
to let anybody know, another member got normal ast/alt by getting vit d normal range, i d follow with intrest as he gets to 70-90ng/ml range

brij116  
1 hour
To: stef2011
I checked my vit d3 level after 2 months of medication. It has improved to a level of (40.30 ng/ml).

I have followed following medication. Calcirol - 60,000 IU (1/week) for six weeks + 1 Shelcal HD daily.

Now I am continuing with the  schedule: Calcirol - 60,000 IU (1/month) for six months + 1 Shelcal HD daily.

This is the shcedule my doctor has prescribed. I do not know why he is giving Shelcal - HD (it has Calcuim -500mg and vit d3 - 500 IU).

Good part it my Liver Function test has come to normal -
AST - 28.0
ALT - 31.0
S. Bilirubin Total : 0.61
Other tests  are also normal
S. Creatine - 1.0
S. Calcium - 9.1

Though, My overall health has improved, but I still feel some giddiness. Doctor says it will take some time to improve since I was suffering from chronic deficiency of Vit d3. (any views Stef ?)

After 15 days i will check my HBSag level and let you know for your further guidance.
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Avatar universal
that's great then... it shoudl be even better with 70/80 ng/ml.. shouldn't it?
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Avatar universal
Yes,

Stef has constantly been advising me to boost my d3 level to improve my HBSag and HBVdna level. Around 2 months back when i checked for d3 level it was only 6.8 ng/ml. So I took Calcirol (60,000 IU) - 1 /week and Shelcal-HD - 1 daily, I have also been taking Probiotic on and of. Now, after two months, my d3 level has come to 40.30 ng/ml with all the Liver Function tests normal (as shown above). I feel much better (though there is still some giddiness at times)

Now, as adivsed by stef I will stop Calcium and continue only with vit d3 and test for d3 level after 15-20 days. Meawhile  I will be cheking my HBSag level to see the impact of improved vit d3 level.
Helpful - 0
Avatar universal
in fact 2 months seems to be a great recovery time.. have you bought vitd3 locally?
Helpful - 0
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