Aa
2nd round HCV treatment
Okie-Dokie;
It took me 6 months to get this together, but I've finally got the 2nd round of Tx going again. Here is a brief overview of round 1:
51 year old Caucasian male
Genotype 1a
Grade 2, stage 3/4
254 lbs
Diabetes M. type 2
Dx with HCV 12/04
Treated with Pegasys/ Copegus total 56 weeks, from 2/05 through 3/06.
Slow viral response at 12 week assay, so increased riba from assigned 1200 mg/day to 1800 mg/day.
Became undetectable to <50 IU by week 20.
Relapsed within 30 days post Tx.
I started round 2 on 9/15/06 with Peg-Intron 0.50 mL/150 mcg/week, and ribavirin 2000 mg/day. For the first three injections, I've been drawing up the entire contents of the IFN vial, after reconstituting with 0.70 mL of the supplied diluent. This has given me an extrapolated dosage of 202 mcg Peg-Intron/week, based on a 0.68 mL injection. Although this IFN dosage isn't officially sanctioned by my new doctor, I have an appointment this Tuesday, and I'll disclose at that time. My three-week labs should be available for review by then, and hopefully will show some positive trends; if not, there's always dose reduction... :-).
Subjectively, I feel fine after three injections; no side effects have shown themselves yet, however this is still *way* early in the game. Last treatment, I was good until week 9 or 10 before this cr@p started creeping up on me, so I guess time will tell the story.
It's probably worth mentioning that I've made some changes regarding exercise and diet as well. As a diabetic, it's important that I maintain tight blood glucose control- particularly while on treatment. Over the last six months, I've managed to lose approx. 50 lbs; walking 8 miles daily in the hills here along with removing most processed foods as well as meats (salmon only now!) from my meals has been really helpful. More and more evidence is suggesting that obesity and insulin resistance are both negative prognostic indicators for SVR, so we'll see if this has any effect in the long run.
I don't expect to be posting very actively; however that just might change if these meds begin slowing me down. Until then, I'm trying to stay as active as possible. I think attitude is an effective tool for Sx; during my last treatment, I resigned myself to the fact that I'd get sick from these meds. This time, I'm going to keep going until I get Gumby-Legs and can't walk... In other words, if the side-effects knock the door off the hinges, I guess they're coming in; however, I'm not going to wait around for them.
My very best to all those folks that I recognize from days past, in addition to a whole lot of new ones as well. Keep plugging away at this stuff, and we'll eventually prevail--
Bill
It took me 6 months to get this together, but I've finally got the 2nd round of Tx going again. Here is a brief overview of round 1:
51 year old Caucasian male
Genotype 1a
Grade 2, stage 3/4
254 lbs
Diabetes M. type 2
Dx with HCV 12/04
Treated with Pegasys/ Copegus total 56 weeks, from 2/05 through 3/06.
Slow viral response at 12 week assay, so increased riba from assigned 1200 mg/day to 1800 mg/day.
Became undetectable to <50 IU by week 20.
Relapsed within 30 days post Tx.
I started round 2 on 9/15/06 with Peg-Intron 0.50 mL/150 mcg/week, and ribavirin 2000 mg/day. For the first three injections, I've been drawing up the entire contents of the IFN vial, after reconstituting with 0.70 mL of the supplied diluent. This has given me an extrapolated dosage of 202 mcg Peg-Intron/week, based on a 0.68 mL injection. Although this IFN dosage isn't officially sanctioned by my new doctor, I have an appointment this Tuesday, and I'll disclose at that time. My three-week labs should be available for review by then, and hopefully will show some positive trends; if not, there's always dose reduction... :-).
Subjectively, I feel fine after three injections; no side effects have shown themselves yet, however this is still *way* early in the game. Last treatment, I was good until week 9 or 10 before this cr@p started creeping up on me, so I guess time will tell the story.
It's probably worth mentioning that I've made some changes regarding exercise and diet as well. As a diabetic, it's important that I maintain tight blood glucose control- particularly while on treatment. Over the last six months, I've managed to lose approx. 50 lbs; walking 8 miles daily in the hills here along with removing most processed foods as well as meats (salmon only now!) from my meals has been really helpful. More and more evidence is suggesting that obesity and insulin resistance are both negative prognostic indicators for SVR, so we'll see if this has any effect in the long run.
I don't expect to be posting very actively; however that just might change if these meds begin slowing me down. Until then, I'm trying to stay as active as possible. I think attitude is an effective tool for Sx; during my last treatment, I resigned myself to the fact that I'd get sick from these meds. This time, I'm going to keep going until I get Gumby-Legs and can't walk... In other words, if the side-effects knock the door off the hinges, I guess they're coming in; however, I'm not going to wait around for them.
My very best to all those folks that I recognize from days past, in addition to a whole lot of new ones as well. Keep plugging away at this stuff, and we'll eventually prevail--
Bill
WHOO HOO!!! HI THERE...SOOOO good to see you!!
This ole fatty just gained 3 lbs out of nowhere...I'm not eating much at all lately, and really felt I had lost quite a bit over the last few weeks (even family said I had lost wheight) so I wheighed myself. HMPH! Yeah right.
This ole fatty just gained 3 lbs out of nowhere...I'm not eating much at all lately, and really felt I had lost quite a bit over the last few weeks (even family said I had lost wheight) so I wheighed myself. HMPH! Yeah right.
That was over a period of 4 years, not dieting. Fat people should never never never diet, best way in the world to gain weight!! That was just making healthier choices,, baked potato or curly fries... well duhh!! Last 20 lbs was on nutrisystem, trying to go low for this tx...haven't gained or lost in 7 months...
Whew Hoo Bill... glad to see your back & started again...
Good For You!!! I hope #2 will be the magical # for you too!
Buckle up that seat belt (the ride still gets bumpy)...You'll be in my thoughts & prays also.... !!!
;)
Good For You!!! I hope #2 will be the magical # for you too!
Buckle up that seat belt (the ride still gets bumpy)...You'll be in my thoughts & prays also.... !!!
;)
TX is a game of second guessing, should ofs couldofs wills... I lost 58 lbs, same reason as yall, but I still have a bmi of 29, so i could have done better.... I think Bill is starting at 2000 mg of riba, so that is a hard hitting dose. wish he was on vertex too.........funny how if it was up to us, we'd fix it all if we could for our fellow heppers..
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